Evidence map›Paper›PMID 37037207›Full record

ArticleThe Lancet. Respiratory medicine2023

Risk and accuracy of outpatient-identified hypoxaemia for death among suspected child pneumonia cases in rural Bangladesh: a multifacility prospective cohort study.

Eric D McCollum, Salahuddin Ahmed, Arunangshu D Roy, Asmd Ashraful Islam, Holly B Schuh, Carina King, Shubhada Hooli, Mohammad Abdul Quaiyum, Amy Sarah Ginsburg, William Checkley and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet. Respiratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 4 countries.

Eric D McCollumGlobal Program in Pediatric Respiratory Sciences, Eudowood Division of Pediatric Respiratory Sciences, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Department of International Health, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. Electronic address: emccoll3@jhmi.edu.
Salahuddin AhmedProjahnmo Research Foundation, Dhaka, Bangladesh.
Arunangshu D RoyProjahnmo Research Foundation, Dhaka, Bangladesh.
Asmd Ashraful IslamProjahnmo Research Foundation, Dhaka, Bangladesh.
Holly B SchuhDepartment of Epidemiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Carina KingDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
Shubhada HooliSection of Emergency Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Mohammad Abdul QuaiyumProjahnmo Research Foundation, Dhaka, Bangladesh; International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Amy Sarah GinsburgClinical Trials Center, University of Washington, Seattle, WA, USA.
William CheckleyDepartment of International Health, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Bloomberg School of Public Health, and Division of Pulmonary and Critical Care, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA; Center for Global Non-Communicable Disease Research and Training, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Abdullah H BaquiDepartment of International Health, International Center for Maternal and Newborn Health, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Tim ColbournInstitute for Global Health, University College London, London, UK.
Biomedical Research Foundation · BDJohns Hopkins University · USBaylor College of Medicine · USJohns Hopkins Medicine · USKarolinska Institutet · SEUniversity College London · GBUniversity of Washington · US

Funding

Pulse oximetry for childhood pneumonia in rural BangladeshK01TW009988 · FIC · JOHNS HOPKINS UNIVERSITY · PI MCCOLLUM, ERIC DOUGLASS · 2014 to 2018
$704k
FIC NIH HHS K01 TW009988
6 · The paper itself

Abstract

backgroundHypoxaemic pneumonia mortality risk in low-income and middle-income countries is high in children who have been hospitalised, but unknown among outpatient children. We sought to establish the outpatient burden, mortality risk, and prognostic accuracy of death from hypoxaemia in children with suspected pneumonia in Bangladesh.

methodsWe conducted a prospective community-based cohort study encompassing three upazila (subdistrict) health complex catchment areas in Sylhet, Bangladesh. Children aged 3-35 months participating in a community surveillance programme and presenting to one of three upazila health complex Integrated Management of Childhood Illness (IMCI) outpatient clinics with an acute illness and signs of difficult breathing (defined as suspected pneumonia) were enrolled in the study; because lower respiratory tract infection mortality mainly occurs in children younger than 1 year, the primary study population comprised children aged 3-11 months. Study physicians recorded WHO IMCI pneumonia guideline clinical signs and peripheral arterial oxyhaemoglobin saturations (SpO

findingsParticipants were recruited between Sept 1, 2015, to Aug 31, 2017. During the study period, a total of 7440 children aged 3-35 months with the first suspected pneumonia episode were enrolled, of whom 3848 (54·3%) with an attempted pulse oximeter measurement and 2-week outcome were included in our primary study population of children aged 3-11-months. Among children aged 3-11 months, an SpO

interpretationThese findings support pulse oximeter use during the outpatient care of young children with suspected pneumonia in Bangladesh as well as the re-evaluation of the WHO IMCI currently recommended threshold of an SpO

fundingFogarty International Center of the National Institutes of Health (K01TW009988), The Bill & Melinda Gates Foundation (OPP1084286 and OPP1117483), and GlaxoSmithKline (90063241).

Indexed as

OutpatientsPneumoniaBangladeshChildChild, PreschoolCohort StudiesHumansHypoxiaOxygenProspective StudiesUnited StatesOxygen

Identifiers

PMID37037207
PMCPMC10469265
OpenAlexW4362706278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.