Evidence map›Paper›PMID 37036971›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex.

Chen-Wei Tsai, Tsung-Yun Liu, Fan-Yi Chao, Yung-Chi Tu, Madison X Rodriguez, Anna M Van Keuren, Zhiwei Ma, John Bankston, Ming-Feng Tsai

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. TMEM65 functions as the mitochondrial NaNature cell biology · 2025
    Article
  5. MICU proteins facilitate CaResearch square · 2025
    Article
  6. Review
  7. Article
  8. MICU1's calcium sensing beyond mitochondrial calcium uptake.Biochimica et biophysica acta. Molecular cell research · 2024
    Review
  9. Mitochondrial Cation Signalling in the Control of Inflammatory Processes.International journal of molecular sciences · 2023
    Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chen-Wei TsaiDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Tsung-Yun LiuDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Fan-Yi ChaoDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Yung-Chi TuDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0009-0007-5074-4883
Madison X RodriguezDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Anna M Van KeurenDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.
Zhiwei MaDalton Cardiovascular Research Center, University of Missouri, Columbia, MO 65211.
John BankstonDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0002-9478-2335
Ming-Feng TsaiDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045.ORCID 0000-0003-4277-1885
University of Colorado Anschutz Medical Campus · USUniversity of Missouri · US

Funding

Dynamics of Acid-sensing ion channelsR35GM137912 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI John Bankston · 2020 to 2026
$2.8M
Molecular mechanisms of the mitochondrial calcium uniporterR01GM129345 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI TSAI, MING-FENG · 2018 to 2022
$1.6M
NIGMS NIH HHS R01 GM129345NIGMS NIH HHS R35 GM137912
6 · The paper itself

Abstract

The mitochondrial calcium uniporter is a Ca

Indexed as

CalciumMitochondrial Membrane Transport ProteinsCalcium-Binding ProteinsCalcium ChannelsCalcium, DietaryMitochondrial MembranesCalciumCalcium-Binding ProteinsCalcium ChannelsCalcium, Dietarymitochondrial calcium uniporterMitochondrial Membrane Transport Proteinscalcium channelsintracellular calcium signalingmitochondrial physiologyorganellar channels

Identifiers

PMID37036971
PMCPMC10120041
OpenAlexW4363678000

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.