Evidence map›Paper›PMID 37036350›Full record

ArticleMicrobiology spectrum2023

Long Noncoding RNA AROD Inhibits Host Antiviral Innate Immunity via the miR-324-5p-CUEDC2 Axis.

Zixiao Zhang, Tianqi Yu, Haimin Li, Liuyang Du, Zian Jin, Xiran Peng, Yan Yan, Jiyong Zhou, Jinyan Gu

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zixiao ZhangKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Tianqi YuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Haimin LiKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Liuyang DuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Zian JinKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Xiran PengKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Yan YanKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.
Jiyong ZhouKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.ORCID 0000-0002-8852-1227
Jinyan GuKey Laboratory of Animal Virology of Ministry of Agriculture, Zhejiang University Center for Veterinary Sciences, Hangzhou, China.ORCID 0000-0002-9763-9569
Zhejiang University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) are a class of noncoding RNAs that are involved in multiple biological processes. Here, we report a mechanism through which the lnc-AROD-miR-324-5p-CUEDC2 axis regulates the host innate immune response, using influenza A virus (IAV) as a model. We identified that host lnc-AROD without protein-coding capability is composed of 975 nucleotides. Moreover, lnc-AROD inhibited interferon-β expression, as well as interferon-stimulated genes ISG15 and MxA. Furthermore,

Indexed as

Influenza A virusMicroRNAsRNA, Long NoncodingAnimalsAntiviral AgentsImmunity, InnateInterferon-betaMiceAntiviral AgentsInterferon-betaMicroRNAsRNA, Long NoncodingCUEDC2innate immunitylnc-ARODmiR-324-5p

Identifiers

PMID37036350
PMCPMC10269697
OpenAlexW4363646338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.