Evidence map›Paper›PMID 37036321›Full record

ReviewAnnals of medicine2023

Research progress and value of albumin-related inflammatory markers in the prognosis of non-small cell lung cancer: a review of clinical evidence.

Chuan-Long Zhang, Meng-Qi Gao, Xiao-Chen Jiang, Xue Pan, Xi-Yuan Zhang, Yi Li, Qian Shen, Yan Chen, Bo Pang

Abstract readReview
In one paragraph

Review in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chuan-Long ZhangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-8485-5537
Meng-Qi GaoWangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-1428-891X
Xiao-Chen JiangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-5711-7803
Xue PanGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0003-0299-7556
Xi-Yuan ZhangGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0003-2910-7373
Yi LiGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0001-5348-422X
Qian ShenGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0002-8066-002X
Yan ChenInternational Medical Department of Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0003-1071-2725
Bo PangInternational Medical Department of Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.ORCID 0000-0001-9664-3972

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory markers have a wide range of predictive values in the prognosis of non-small lung cancer (NSCLC). Poor nutritional status usually means a poor prognosis in patients with NSCLC, which is widely recognized by oncologists and nutritionists. Serum albumin has a certain value in evaluating the prognosis of patients. Several inflammatory albumin-related markers have been proposed, but they have not been widely used in predicting the prognosis of NSCLC in clinical practice. We aim to systematically review the published clinical evidence of albumin-related inflammatory markers in predicting the prognosis of NSCLC and to describe their progress and value. The results showed that the markers included in the review could be prognostic indicators in patients with NSCLC. However, we found that the cut-off value of albumin-related inflammatory markers with quantitative nature was very chaotic and needed to be defined by recognized standards. We summarized and compared the advantages and disadvantages of these markers, but a prospective cohort study with long-term follow-up after adjustment for important confounders is still necessary. Whether the results and conclusions could be directly applied in clinical practice needs to be identified and evaluated. There is an urgent need to classify and standardize the albumin-related inflammatory markers that play an important role in the prognosis of NSCLC, which is the key to ensuring the transformation from clinical study to clinical application.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsBiomarkersHumansPrognosisProspective StudiesRetrospective StudiesSerum AlbuminBiomarkersSerum AlbuminalbumininflammationmarkersNon-small lung cancerprognosis

Identifiers

PMID37036321
PMCPMC10088931

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.