Evidence map›Paper›PMID 37036298›Full record

ArticleAmerican journal of physiology. Cell physiology2023

Bicarbonate is the primary inducer of KCC3a expression in renal cortical B-type intercalated cells.

Mohammed Z Ferdaus, Andrew S Terker, Rainelli Koumangoye, Susan M Wall, Eric Delpire

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Sex differences in renal acid-base regulation.Current opinion in nephrology and hypertension · 2026
    Review
  2. Review
  3. Article
  4. Novel functions of the anion exchanger AE4 (SLC4A9).Pflugers Archiv : European journal of physiology · 2024
    Review
  5. Secretin: a hormone for HCOPflugers Archiv : European journal of physiology · 2024
    Review
  6. Article
  7. Article
  8. The K-Cl cotransporter-3 in the mammalian kidney.Current opinion in nephrology and hypertension · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mohammed Z FerdausDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States.ORCID 0000-0002-4860-5506
Andrew S TerkerDivision of Nephrology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States.ORCID 0000-0003-1498-9043
Rainelli KoumangoyeDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States.ORCID 0000-0002-5963-8987
Susan M WallDivision of Nephrology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, United States.ORCID 0000-0003-2786-8849
Eric DelpireDepartment of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States.ORCID 0000-0002-3702-1599
Vanderbilt University · USEmory University · US

Funding

WNK-SPAK signaling in the Distal NephronR01DK093501 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, Paul A Welling · 2012 to 2026
$12.1M
OXGR1 in Renal Intercalated Cells, Salt Transport and Diuretic EfficacyR01DK110375 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Eric J Delpire, SUSAN MARIE WALL · 2017 to 2026
$6.7M
Innovative therapeutic approaches to treat chronic kidney diseaseDP5OD033412 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TERKER, ANDREW S. · 2022 to 2025
$2.2M
Regulation of intercalated cell function by the mineralocorticoid receptorR01DK119793 · NIDDK · EMORY UNIVERSITY · PI WALL, SUSAN MARIE · 2019 to 2022
$1.6M
NIDDK NIH HHS R01 DK093501NIDDK NIH HHS R01 DK110375NIDDK NIH HHS R01 DK119793NIH HHS DP5 OD033412
6 · The paper itself

Abstract

A primary function of intercalated cells in the distal tubule of the kidney is to maintain pH homeostasis. For example, type B intercalated cells secrete bicarbonate largely through the action of the apical Cl

Indexed as

AlkalosisBicarbonatesAldosteroneAngiotensin IIAnimalsAnion Transport ProteinsKidneyMiceSulfate TransportersAldosteroneAngiotensin IIAnion Transport ProteinsBicarbonatesSulfate Transportersalkalemiabicarbonateintercalated cellsK-Cl cotransportpendrin

Identifiers

PMID37036298
PMCPMC10191129
OpenAlexW4363643592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.