Evidence map›Paper›PMID 37036063›Full record

ArticlePharmaceutical biology2023

The protective effect of 999 XiaoErGanMao granules on the lungs and intestines of influenza A virus-infected mice.

Yuan-Zhen Hao, Li-Feng Cen, Ting Wang, Tong Yi, Xun-Long Shi, Hui-Juan Duan, Zhi Dai, Hai-Yan Zhu, Jian-Guo Tang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yuan-Zhen HaoDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.
Li-Feng CenDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.
Ting WangDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.
Tong YiDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.
Xun-Long ShiDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.ORCID 0000-0002-7009-5629
Hui-Juan DuanChina Resources Sanjiu Medical & Pharmaceutical Co., Ltd, Shenzhen, China.
Zhi DaiChina Resources Sanjiu Medical & Pharmaceutical Co., Ltd, Shenzhen, China.
Hai-Yan ZhuDepartment of Biological Medicines & Shanghai Engineering Research Center of ImmunoTherapeutics, School of Pharmacy, Fudan University, Shanghai, China.
Jian-Guo TangDepartment of Trauma-Emergency & Critical Care Medicine, Shanghai Fifth People's Hospital, Fudan University, Shanghai, China.
Fudan University · CNChina Resources (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextGastrointestinal symptoms are a common complication of influenza virus infection in children, which the gut-lung axis become involved in its biological progress. The protective effect of 999 XiaoErGanMao granules (XEGMG) on multi-organ injury in viral pneumonia remains unclear.

objectiveTo investigate the therapeutic effect of XEGMG on lungs and intestines injury in A/FM/1/47 (H1N1) influenza virus-infected mice. MATERIALS AND

methodsMale BALB/c mice were infected with the 2LD

resultsTreating with XEGMG (12 g/kg) can mitigate body weight loss caused by 2LD DISCUSSION AND

conclusionsXEGMG can protect against H1N1 invasion involved in gut-lung axis regulation. The results provide new evidence for the protective effect of XEGMG, which is beneficial to vulnerable children.

Indexed as

Influenza A virusInfluenza A Virus, H1N1 SubtypeAnimalsCytokinesIntestinesLungMaleMiceMice, Inbred BALB CCytokinesInfluenza virusintestines injuryviral pneumonia

Identifiers

PMID37036063
PMCPMC10088977
OpenAlexW4363646108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.