Evidence map›Paper›PMID 37035505›Full record

ArticleFrontiers in neural circuits2023

Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons.

Adam J Granger, Karen Mao, Jessica L Saulnier, Morgan E Hines, Bernardo L Sabatini

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  3. Article
  4. Neuroprotective role of DNTαβ Cell transplantation on modulating immune microenvironment in spinal cord injured mice.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Adam J GrangerDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Karen MaoDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Jessica L SaulnierDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Morgan E HinesDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Bernardo L SabatiniDepartment of Neurobiology, Harvard Medical School, Boston, MA, United States.
Harvard University · US

Funding

Action and interaction of ionotropic and metabotropic neurotransmissionR37NS046579 · NINDS · HARVARD MEDICAL SCHOOL · PI SABATINI, BERNARDO L · 2018 to 2024
$4.6M
Synaptic connectivity of Basal Forebrain neurotransmitter systemsK99NS102429 · NINDS · HARVARD MEDICAL SCHOOL · PI GRANGER, ADAM · 2018 to 2019
$179k
NINDS NIH HHS K99 NS102429NINDS NIH HHS R37 NS046579
6 · The paper itself

Abstract

Acetylcholine and GABA are often co-released, including from VIP-expressing neurons of the cortex, cortically-projecting neurons of the globus pallidus externus and basal forebrain, and hippocampal-projecting neurons of the medial septum. The co-release of the functionally antagonistic neurotransmitters GABA and acetylcholine (ACh) greatly expands the possible functional effects of cholinergic neurons and provides an additional exogenous source of inhibition to the cortex. Transgene expression suggests that nearly all forebrain cholinergic neurons in mice at some point in development express

Indexed as

Acetylcholinegamma-Aminobutyric AcidAnimalsCerebral CortexCholine O-AcetyltransferaseCholinergic NeuronsGene ExpressionIn Situ Hybridization, FluorescenceMiceAcetylcholineCholine O-Acetyltransferasegamma-Aminobutyric Acidacetylcholinecholinergic transmissionGABAGABAergic transmissionneurotransmitter co-transmission

Identifiers

PMID37035505
PMCPMC10080005
OpenAlexW4360866240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.