Evidence map›Paper›PMID 37035453›Full record

ArticleHepatoma research2023

Hepatocellular carcinoma in Pacific Islanders: comparison of Pacific Island-born

Shelby K Yee, Brenda Y Hernandez, Sandi Kwee, Linda L Wong

Open access · diamondAbstract read
In one paragraph

Article in Hepatoma research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. The Changing Pathogenesis of Liver Cancer in Hawaii over Three Decades.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shelby K YeeDepartment of Surgery, John A. Burns School of Medicine, Honolulu, HI 96813, USA.
Brenda Y HernandezUniversity of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Sandi KweeUniversity of Hawaii Cancer Center, Honolulu, HI 96813, USA.
Linda L WongDepartment of Surgery, John A. Burns School of Medicine, Honolulu, HI 96813, USA.
University of Hawaiʻi at Mānoa · USUniversity of Hawaii System · US

Funding

University of Guam/Cancer Research Center of Hawaii Partnership (2 of 2)U54CA143728 · NCI · UNIVERSITY OF GUAM · PI Laura Biggs · 2009 to 2026
$20.1M
University of Guam/Cancer Research Center of Hawaii Partnership (1 of 2)U54CA143727 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Kevin Darryl Cassel · 2009 to 2026
$19.1M
Pathway Specific Functional Biomarkers for the Early Detection of Liver CancerU01CA230690 · NCI · GEORGE WASHINGTON UNIVERSITY · PI MISHRA, LOPA, SHETTY, KIRTI · 2018 to 2022
$3.4M
NCI NIH HHS U01 CA230690NCI NIH HHS U54 CA143727NCI NIH HHS U54 CA143728
6 · The paper itself

Abstract

Aim: To describe demographic, clinical, and outcome differences in Pacific Island-born (PI-born) compared to US-born hepatocellular carcinoma (HCC) patients of Pacific Island ancestry within a clinical cohort in Hawaii. Methods: A prospectively collected database of 1608 patients diagnosed with HCC over a 30-year period (1993-2022) identified 252 patients of Pacific Islander ethnicity. Data collected: demographics, medical history, laboratory data, tumor characteristics, treatment, and survival. Patients were divided into two groups: PI-born and US-born. Categorical variables were analyzed using ANOVA and chi-square analysis. Odds ratios with 95% confidence intervals were calculated using univariate and multivariate logistic regression. Overall survival was evaluated using Kaplan-Meier analysis. Results: PI-born patients were younger (57.3 Conclusion: HBV remains the primary risk factor for HCC in PI-born patients, whereas HCC in US-born patients is more associated with the adoption of a Westernized lifestyle.

Indexed as

hepatocellular carcinomaliver resectionliver transplantnativityPacific Islanderrisk factors

Identifiers

PMID37035453
PMCPMC10079260
OpenAlexW4327648131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.