ArticleFrontiers in oncology2023
Identification and diagnosis of mammographic malignant architectural distortion using a deep learning based mask regional convolutional neural network.
Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 8 citations in OpenAlex.
- Combination of Deep Learning Grad-CAM and Radiomics for Automatic Localization and Diagnosis of Architectural Distortion on DBT.Academic radiology · 2025Article
- Personalized predictions of neoadjuvant chemotherapy response in breast cancer using machine learning and full-field digital mammography radiomics.Frontiers in medicine · 2025Article
- Image segmentation for pest detection of crop leaves by improvement of regional convolutional neural network.Scientific reports · 2024Article
- Machine learning and new insights for breast cancer diagnosis.The Journal of international medical research · 2024Review
- Identification of Adolescent Menarche Status Using Biplanar X-ray Images: A Deep Learning-Based Method.Bioengineering (Basel, Switzerland) · 2023Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
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Abstract
Background: Architectural distortion (AD) is a common imaging manifestation of breast cancer, but is also seen in benign lesions. This study aimed to construct deep learning models using mask regional convolutional neural network (Mask-RCNN) for AD identification in full-field digital mammography (FFDM) and evaluate the performance of models for malignant AD diagnosis. Methods: This retrospective diagnostic study was conducted at the Second Affiliated Hospital of Guangzhou University of Chinese Medicine between January 2011 and December 2020. Patients with AD in the breast in FFDM were included. Machine learning models for AD identification were developed using the Mask RCNN method. Receiver operating characteristics (ROC) curves, their areas under the curve (AUCs), and recall/sensitivity were used to evaluate the models. Models with the highest AUCs were selected for malignant AD diagnosis. Results: A total of 349 AD patients (190 with malignant AD) were enrolled. EfficientNetV2, EfficientNetV1, ResNext, and ResNet were developed for AD identification, with AUCs of 0.89, 0.87, 0.81 and 0.79. The AUC of EfficientNetV2 was significantly higher than EfficientNetV1 (0.89 vs. 0.78, P=0.001) for malignant AD diagnosis, and the recall/sensitivity of the EfficientNetV2 model was 0.93. Conclusion: The Mask-RCNN-based EfficientNetV2 model has a good diagnostic value for malignant AD.
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