Evidence map›Paper›PMID 37035125›Full record

ArticlePlastic and reconstructive surgery. Global open2023

A Consensus Approach for Targeted Muscle Reinnervation in Amputees.

Kyle R Eberlin, David A Brown, R Glenn Gaston, Grant M Kleiber, Jason H Ko, Stephen J Kovach, Bryan J Loeffler, Brendan J MacKay, Benjamin K Potter, Margaret S Roubaud and 3 more

Open access · goldAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Algorithm for Surgical Management of Symptomatic Hand and Digital Neuromas.Plastic and reconstructive surgery. Global open · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Neuroma Prevention by Nerve to Artery Coaptation: A Pilot Study.Journal of hand surgery global online · 2026
    Article
  7. Active Nerve Management for Below-knee Amputation: A Comparison of Approaches.Plastic and reconstructive surgery. Global open · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Targeted muscle reinnervation in upper extremity amputations.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Review
  13. Article
  14. Article
  15. Three Useful Tips and Tricks for Intraoperative Nerve Stimulation.Plastic and reconstructive surgery. Global open · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Kyle R EberlinDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
David A BrownDivision of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, Durham, N.C.
R Glenn GastonOrthoCarolina Hand and Upper Extremity Department and Atrium Health Department of Orthopedic Surgery, Charlotte, N.C.
Grant M KleiberDepartment of Plastic Surgery, MedStar Georgetown University Hospital, Washington, D.C.
Jason H KoDivision of Plastic and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Stephen J KovachDivision of Plastic Surgery, Department of Orthopaedic Surgery, University of Pennsylvania Health System, Philadelphia, Pa.
Bryan J LoefflerOrthoCarolina Hand and Upper Extremity Department and Atrium Health Department of Orthopedic Surgery, Charlotte, N.C.
Brendan J MacKayDepartment of Orthopedic Surgery, Texas Tech University Health Science Center, Lubbock, Tex.
Benjamin K PotterUniformed Services University - Walter Reed Department of Surgery, Bethesda, Md.
Margaret S RoubaudDepartment of Plastic and Reconstructive Surgery, University of Texas MD Anderson Cancer Center, Houston, Tex.
Jason M SouzaDepartment of Plastic and Reconstructive Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Ian L ValerioDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Mass.
Gregory A DumanianDivision of Plastic and Reconstructive Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.
The Ohio State University Wexner Medical Center · US

Funding

Spatial Core (Moffit)U19NS130617 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI William Russell Renthal, CLIFFORD J WOOLF · 2022 to 2026
$15.5M
6 · The paper itself

Abstract

Amputations have been performed with few modifications since the dawn of surgery. Blood vessels are ligated, bones are shortened, and nerves are cut. In a percentage of people, this can result in severe neuropathic, residual limb, and phantom limb pain. Targeted muscle reinnervation is a surgical procedure initially conceived to optimize function for myoelectric prostheses in amputees. Recently, it has been adopted more widely by surgeons for the prevention and treatment of neuropathic pain. Perhaps as a function of its relatively recent development, many authors perform this operation differently, and there has been no overall agreement regarding the principles, indications, technical specifics, and postoperative management guidelines. This article is written as a consensus statement by surgeons focused on the treatment of neuropathic pain and those with extensive experience performing targeted muscle reinnervation. It is designed to serve as a roadmap and template for extremity surgeons to consider when performing targeted muscle reinnervation.

Identifiers

PMID37035125
PMCPMC10079335
OpenAlexW4362603855

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.