Evidence map›Paper›PMID 37034895›Full record

ArticleAvicenna journal of medical biotechnology

Human T2R38 Bitter Taste Receptor Expression and COVID-19: From Immunity to Prognosis.

Lakshmi Deepak Bethineedi, Hediyeh Baghsheikhi, Afsaneh Soltani, Zahedeh Mafi, Noosha Samieefar, Shaikh Sanjid Seraj, Mohammad Amin Khazeei Tabari

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Important Role of Interleukin-2 in COVID-19.Journal of immunology research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lakshmi Deepak BethineediAndhra Medical College, Visakhapatnam, Andhra Pradesh, India.
Hediyeh BaghsheikhiStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Afsaneh SoltaniStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zahedeh MafiStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Noosha SamieefarStudent Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shaikh Sanjid SerajWalsall Healthcare NHS Trust, Walsall Manor Hospital, Walsall, United Kingdom.
Mohammad Amin Khazeei TabariStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Universal Scientific Education and Research Network · IRShahid Beheshti University of Medical Sciences · IRAndhra University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bitter taste-sensing type 2 receptor (T2Rs or TAS2Rs) found on ciliated epithelial cells and solitary chemosensory cells have a role in respiratory tract immunity. T2Rs have shown protection against SARS-CoV-2 by enhancing the innate immune response. The purpose of this review is to outline the current sphere of knowledge regarding this association. Methods: A narrative review of the literature was done by searching (T2R38 OR bitter taste receptor) AND (COVID-19 OR SARS-CoV-2) keywords in PubMed and google scholar. Results: T2R38, an isoform of T2Rs encoded by the Conclusion: This review reveals that patients' innate immune response to SARS-COV-2 could be influenced by T2R38 receptor allelic variations.

Indexed as

Bitter taste receptors (T2Rs)Coronavirus diseaseCOVID-19InfectionT2R38

Identifiers

PMID37034895
PMCPMC10073923
OpenAlexW4322100242

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.