Evidence map›Paper›PMID 37034833›Full record

ArticleFrontiers in neuroanatomy2023

Ricardo Insausti, Ana María Insausti, Mónica Muñoz López, Isidro Medina Lorenzo, Maria Del Mar Arroyo-Jiménez, María Pilar Marcos Rabal, Carlos de la Rosa-Prieto, José Carlos Delgado-González, Javier Montón Etxeberria, Sandra Cebada-Sánchez and 11 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 3 countries.

Ricardo InsaustiHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Ana María InsaustiDepartment of Health, School of Medicine, Public University of Navarra, Pamplona, Spain.
Mónica Muñoz LópezHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Isidro Medina LorenzoHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Maria Del Mar Arroyo-JiménezHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
María Pilar Marcos RabalHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Carlos de la Rosa-PrietoHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
José Carlos Delgado-GonzálezHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Javier Montón EtxeberriaHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Sandra Cebada-SánchezHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Juan Francisco Raspeño-GarcíaHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
María Mercedes Iñiguez de OnzoñoHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Francisco Javier Molina RomeroHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
Ruth Benavides-PiccioneLaboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, and Instituto Cajal, CSIC, Madrid, Spain.
Silvia Tapia-GonzálezLaboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, and Instituto Cajal, CSIC, Madrid, Spain.
Laura E M WisseDepartment of Diagnostic Radiology, Lund University, Lund, Sweden.
Sadhana RavikumarDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, United States.
David A WolkDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, United States.
Javier DeFelipeLaboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, and Instituto Cajal, CSIC, Madrid, Spain.
Paul YushkevichDepartment of Radiology, University of Pennsylvania, Philadelphia, PA, United States.
Emilio Artacho-PérulaHuman Neuroanatomy Laboratory, Neuromax CSIC Associated Unit, Medical Sciences Department, School of Medicine and CRIB, University of Castilla La Mancha, Albacete, Spain.
University of Castilla-La Mancha · ESUniversity of Pennsylvania · USInstituto Cajal · ESLund University · SEUniversidad de Navarra · ESUniversidad Politécnica de Madrid · ES

Funding

Research Education ComponentP30AG072979 · NIA · UNIVERSITY OF PENNSYLVANIA · PI DAVID A WOLK · 2021 to 2026
$24.8M
Ex Vivo Imaging of the Aging Brain to Discover Morphology/Pathology AssociationsR01AG056014 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Paul A. Yushkevich · 2017 to 2026
$4.5M
Ex Vivo Imaging of the Aging Brain to Discover Morphology/Pathology AssociationsRF1AG056014 · NIA · UNIVERSITY OF PENNSYLVANIA · PI YUSHKEVICH, PAUL A. · 2023 to 2023
$2.1M
NIA NIH HHS P30 AG072979NIA NIH HHS R01 AG056014NIA NIH HHS RF1 AG056014
6 · The paper itself

Abstract

We present a method for human brain fixation based on simultaneous perfusion of 4% paraformaldehyde through carotids after a flush with saline. The left carotid cannula is used to perfuse the body with 10% formalin, to allow further use of the body for anatomical research or teaching. The aim of our method is to develop a vascular fixation protocol for the human brain, by adapting protocols that are commonly used in experimental animal studies. We show that a variety of histological procedures can be carried out (cyto- and myeloarchitectonics, histochemistry, immunohistochemistry, intracellular cell injection, and electron microscopy). In addition,

Indexed as

carotid perfusionelectron microscopyfixationhistologyhuman brainintracellular injectionMRI

Identifiers

PMID37034833
PMCPMC10076536
OpenAlexW4360617093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.