Evidence map›Paper›PMID 37034564›Full record

ArticleObesity science & practice2023

Immunohistochemical analysis of caspase expression in the brains of individuals with obesity or overweight.

Erick Gómez-Apo, Juan Silva-Pereyra, Virgilia Soto-Abraham, Alejandra Mondragón-Maya, Javier Sanchez-Lopez

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Erick Gómez-ApoServicio de Anatomía Patológica Hospital General de México "Dr. Eduardo Liceaga" Ciudad de México México.
Juan Silva-PereyraFacultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México.
Virgilia Soto-AbrahamServicio de Anatomía Patológica Hospital General de México "Dr. Eduardo Liceaga" Ciudad de México México.
Alejandra Mondragón-MayaFacultad de Estudios Superiores Iztacala Universidad Nacional Autónoma de México Tlalnepantla México.
Javier Sanchez-LopezEscuela Nacional de Estudios Superiores Unidad Juriquilla Universidad Nacional Autónoma de México Querétaro México.ORCID https://orcid.org/0000-0002-4291-0315
Autonomous University of Tlaxcala · MXHospital General de México · MXUniversidad Autónoma de la Ciudad de México · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms underlying the negative effects of obesity on the brain are still unknown. Obesity is associated with oxidative stress in the brain and neuroinflammation that promotes neurodegenerative diseases. Chronic low-grade neuroinflammation in obesity could be associated with lower volumes of gray matter and lower neuronal density. If neuroinflammation mediated by the expression of cytokines and chemokines leads to apoptosis, this can be assessed by examining caspase expression. The aim of this study was to compare the expression of caspases in the 16 brains of donors with obesity/overweight (

Indexed as

caspase‐1caspase‐8caspasesimmunohistochemicalneuroinflammation

Identifiers

PMID37034564
PMCPMC10073824
OpenAlexW4289841302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.