Evidence map›Paper›PMID 37034559›Full record

ArticleObesity science & practice2023

A pilot randomized controlled trial of liraglutide 3.0 mg for binge eating disorder.

Kelly C Allison, Ariana M Chao, Maija B Bruzas, Courtney McCuen-Wurst, Elizabeth Jones, Cooper McAllister, Kathryn Gruber, Robert I Berkowitz, Thomas A Wadden, Jena S Tronieri

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Bulimia nervosa.Nature reviews. Disease primers · 2026
    Review
  7. Review
  8. Review
  9. Review
  10. Observational
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Pharmacological management of binge eating disorder.The mental health clinician · 2025
    Article
  17. Review
  18. GLP-1 Receptor Agonists and Research to Treat Overeating and Substance Use Disorders.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kelly C AllisonDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0002-9807-0220
Ariana M ChaoDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Maija B BruzasDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Courtney McCuen-WurstDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Elizabeth JonesDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Cooper McAllisterDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Kathryn GruberDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Robert I BerkowitzDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
Thomas A WaddenDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.ORCID https://orcid.org/0000-0002-0438-4609
Jena S TronieriDepartment of Psychiatry Perelman School of Medicine at the University of Pennsylvania Philadelphia Pennsylvania USA.
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Improving Weight Loss in Early Non-responders to Behavioral TreatmentK23DK116935 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI TRONIERI, JENNIFER SHAW · 2019 to 2023
$938k
NIDDK NIH HHS K23 DK116935
6 · The paper itself

Abstract

Objective: To assess the efficacy of liraglutide 3.0 mg, a glucagon-like peptide-1 (GLP-1) receptor agonist, for binge eating disorder (BED). Methods: Adults with a body mass index (BMI) ≥ 27 kg/m Results: Participants ( Conclusion: Participants in both groups reported reductions in OBEs, with the liraglutide group showing clinically meaningful weight loss. A pharmacy medication dispensing error was a significant limitation of this study. Further research on liraglutide and other GLP-1 agonists for BED is warranted.

Indexed as

binge eating disorderbinge episodeseating disorderliraglutideloss of control eatingweight loss medication

Identifiers

PMID37034559
PMCPMC10073825
OpenAlexW4282044710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.