Evidence map›Paper›PMID 37034531›Full record

ArticleArchives of medical science : AMS2023

Telomere-telomerase system status in patients with acute myocardial infarction with ST-segment elevation - relationship with oxidative stress.

Aleksandra Vukašinović, Barbara Ostanek, Aleksandra Klisic, Srdjan Kafedžić, Marija Zdravković, Ivan Ilić, Miron Sopić, Saša Hinić, Milica Stefanović, Lidija Memon and 6 more

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Aleksandra VukašinovićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Barbara OstanekDepartment of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Aleksandra KlisicPrimary Health Care Center, University of Montenegro, Faculty of Medicine, Podgorica, Montenegro.
Srdjan KafedžićDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Marija ZdravkovićFaculty of Medicine, University of Belgrade, Belgrade, Serbia.
Ivan IlićDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Miron SopićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Saša HinićDepartment of Cardiology, Clinical Hospital Center Bezanijska kosa, Belgrade, Serbia.
Milica StefanovićDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Lidija MemonClinical Chemistry Laboratory, Clinical Hospital Center Bezanijska kosa, Belgrade, Serbia.
Branka GakovićDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Nataša Bogavac-StanojevićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Vesna Spasojević-KalimanovskaDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.
Janja MarcDepartment of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia.
Aleksandar N NeškovićDepartment of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia.
Jelena Kotur-StevuljevićDepartment of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Telomeres are protective chromosomal ends. Short telomeres are a proven biomarker of biological aging. We aimed to find an association of telomere length and telomerase activity in circulating leukocytes and thromboaspirates of patients with acute myocardial infarction. Furthermore, association of the telomere-telomerase system with oxidative stress markers (as common risk factors for coronary artery disease (CAD)) was tested. Material and methods: Patients were selected from the patients admitted to the intensive care unit with acute myocardial infarction with ST-segment elevation (STEMI), with the following inclusion criteria - STEMI patients between 18 and 80 years old of both genders and candidates for primary percutaneous coronary intervention, with infarction pain present for a maximum of 12 h. In all the patients leukocyte telomere length, telomerase activity and scores related to oxidative-stress status (Protective, Damage and OXY) were evaluated. Results: Patients were divided into different groups: with stable angina pectoris (AP) ( Conclusions: Leukocyte telomere length and telomerase activity can differentiate CAD patients from healthy persons, and relate CAD to oxidative stress.

Indexed as

cardiovascular diseaseoxidative stresstelomerase activitytelomere length

Identifiers

PMID37034531
PMCPMC10074292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.