ArticleOTA international : the open access journal of orthopaedic trauma2023
Early hip fracture surgery is safe for patients on direct oral anticoagulants.
Article in OTA international : the open access journal of orthopaedic trauma, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Superior Gluteal Artery Injury After Cephalomedullary Nailing of a Hip Fracture in a Patient on Anticoagulation: A Case Report and Literature Review.Journal of orthopaedic case reports · 2026Article
- Hidden blood loss after proximal femur fractures fixation: analysis of the first three postoperative days and influence of anticoagulants.Archives of orthopaedic and trauma surgery · 2026Article
- Perioperative Anemia and Transfusion Management in Older Adults with Osteoporotic Hip Fractures: A Narrative Review of Current Evidence and Emerging Strategies.Clinical interventions in aging · 2026Review
- Does ongoing antithrombotic therapy increase the risk of revision after trochanteric fracture fixation? A retrospective cohort study with competing risk analyses.Archives of orthopaedic and trauma surgery · 2025Article
- The impact of direct oral anticoagulants on hip fracture care in Australia and New Zealand: a prospective patient sprint audit.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Impact of anticoagulation therapy on surgical timing, hospital stay, and postoperative outcomes in proximal femur fracture patients.Acta orthopaedica et traumatologica turcica · 2025Article
- Transfusion Risk Factors in Low-Energy Pelvic Fractures: A Retrospective Cohort Study.Geriatric orthopaedic surgery & rehabilitation · 2025Article
- Proximal Femur Fractures: Evaluating the Necessity of On-Call Surgery.Journal of clinical medicine · 2024Article
- The management of anticoagulated fragility femoral fracture patients.Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2024Review
- Early Hip Fracture Surgery in Patients Taking Direct Oral Anticoagulants Improves Outcome.Journal of clinical medicine · 2024Article
- The Safety and Efficacy of Microporous Polysaccharide Hemospheres in Terms of the Complication Rates in Total Hip Arthroplasty for Femoral Neck Fractures: A Control-Matched Retrospective Cohort.Life (Basel, Switzerland) · 2024Article
- Management and 1-Year Outcome in Elderly Patients with Hip Fracture Surgery Receiving Anticoagulation (Warfarin or DOAc) or P2Y12 Antiplatelet Agents.Journal of clinical medicine · 2023Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objectives: To determine how preoperative direct oral anticoagulant (DOAC) use affects rates of blood transfusion, clinically important blood loss, and 30-day mortality in patients with hip fracture undergoing surgery within 48 hours of presentation to the emergency department. Design: Retrospective cohort study. Setting: Academic trauma center. Patients: A total of 535 patients with hip fracture who underwent open cephalomedullary nail fixation or arthroplasty either taking a direct oral anticoagulant or no form of chemical anticoagulant/antiplatelet agent before presentation (control). Main Outcome Measures: Demographics, time to surgery, type of surgery, blood transfusion requirement, clinically important blood loss, and 30-day mortality. Results: Forty-one patients (7.7%) were taking DOACs. DOAC patients were older (81.7 vs. 77 years, Conclusions: Our results suggest that early surgery may be safe in patients with hip fracture taking DOACs despite theoretical risk of increased bleeding. Because early surgery has previously been associated with decreased morbidity and mortality, we suggest that hip fracture surgery should not be delayed because a patient is taking direct oral anticoagulants. Level of Evidence: Prognostic Level III.
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Registered trials
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