Evidence map›Paper›PMID 37034339›Full record

ArticleFrontiers in cardiovascular medicine2023

Elevated albumin corrected anion gap is associated with poor in-hospital prognosis in patients with cardiac arrest: A retrospective study based on MIMIC-IV database.

Beiping Hu, Lei Zhong, Meng Yuan, Jie Min, Lili Ye, Jianhong Lu, Xiaowei Ji

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

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0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Beiping HuDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Lei ZhongDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Meng YuanDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Jie MinDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Lili YeDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Jianhong LuDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.
Xiaowei JiDepartment of Intensive Care Unit, Huzhou Central Hospital, the Affiliated Huzhou Hospital of Zhejiang University School of Medicine, Huzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiac arrest(CA) is one of the most leading causes of death. Most of the indicators which used to predict the prognosis of patients with CA are not recognized. Previous studies have suggested that albumin corrected anion gap (ACAG) is associated with recovery of spontaneous circulation in patients with CA, but the predictive value of ACAG for prognosis has not been investigated. This study aims to explore the relationship between ACAG and prognosis during hospitalization in patients with CA. Methods: The baseline data of adult patients with CA hospitalized in the intensive care unit (ICU) from 2008 to 2019 in the American Intensive Care Database (MIMIC-IV, version v2.0) were collected. According to the in-hospital prognosis, patients were divided into survival and non-survival group. Based on the criteria of ACAG level in the previous literature, patients enrolled were divided into normal ACAG (12-20 mmol/L) and high ACAG (>20 mmol/L) group. The basic information of patients during hospitalization were compared and analyzed between the two groups with propensity score matching (PSM). The Kaplan-Meier method was used to compare the cumulative survival rates of normal ACAG and high ACAG groups before and after matching. Restricted cubic spline (RCS) method and multivariate COX proportional hazards regressions were used to analyze whether elevated ACAG was associated with all-cause mortality during hospitalization. Results: A total of 764 patients were included. A matched cohort ( Conclusions: Elevated ACAG is associated with increased all-cause mortality in patients with CA during hospitalization, it can be an independent risk factor for poor prognosis in patients with CA and remind clinicians to pay more attention to these patients.

Indexed as

albumin corrected anion gapcardiac arrestintensive care unitMIMIC-IV databaseprognosis

Identifiers

PMID37034339
PMCPMC10076801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.