ArticleFrontiers in cardiovascular medicine2023
Helical flow in tortuous aortas and its relationship to turbulence: A whole-aorta 4D flow MRI study.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Aortic Valve Phenotype Shapes Helical Flow in the Ascending Aorta: Insights from 4D Flow MRI.Annals of biomedical engineering · 2026Article
- Patient-Specific Fluid-Structure Interaction Simulations Suggest Wall-Shear-Stress-Related Biomarkers in Type B Dissection Associated with Marfan Syndrome.Annals of biomedical engineering · 2026Article
- Computer-aided assessment of intracranial arterial tortuosity as a predictor of aneurysm occurrence and instability.Neuroradiology · 2026Article
- 4D Flow MRI Velocity and Turbulence Mapping in Mild Valvular Heart Disease.Journal of magnetic resonance imaging : JMRI · 2026Observational
- Multimodality comparison of aorta morphology in patients with aortopathy: 4D flow CMR, CTA, mDIXON.BMC medical imaging · 2025Article
- Relationship of the lumbar Lordotic angle to the abdominal aortic deviation and abdominal aortic diameter.Scientific reports · 2025Article
- Evaluation of the presence and severity of spontaneous splenorenal or gastrorenal shunts via four-dimensional flow magnetic resonance imaging: a preliminary study.Quantitative imaging in medicine and surgery · 2024Article
- Numerical simulation and in vitro experimental study of the hemodynamic performance of vena cava filters with helical forms.Scientific reports · 2024Article
- Haemodynamic changes in visceral hybrid repairs of type III and type V thoracoabdominal aortic aneurysms.Scientific reports · 2023Article
- Four-Dimensional Flow MRI for the Evaluation of Aortic Endovascular Graft: A Pilot Study.Diagnostics (Basel, Switzerland) · 2023Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Increased vascular tortuosity is a hallmark of ageing of the vascular system, including the aorta. However, the impact of tortuosity on aortic blood flow is unknown. We hypothesized that increased tortuosity would be associated with increased blood flow helicity and with decreased degree of blood flow turbulence as measured by the turbulent kinetic energy (TKE). Methods: 4D Flow MR images covering the entire aorta from the aortic valve to the iliac bifurcation were acquired in 23 normal volunteers aged 18-30 years ("Young") and 23 normal volunteers aged 66-76 years ("Old") without aortic disease. The aorta was segmented and divided into four regions: the ascending, descending, suprarenal abdominal and infrarenal abdominal aorta. Tortuosity, helicity, TKE, flow velocity, and Reynolds number were computed for the whole aorta and for each section. Results: Tortuosity and helicity were higher whereas TKE, velocity, and Reynolds number were lower in Old than in Young, for all aortic regions ( Conclusion: Tortuosity increases with age and blood flow in tortuous aortas is more helical. Increasing helicity, in turn, is associated with decreasing TKE.
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