Evidence map›Paper›PMID 37034004›Full record

ArticleHemaSphere2023

Outcomes of Patients With Classic Hodgkin Lymphoma Who Relapsed After Autologous Stem Cell Transplant.

Aung M Tun, Yucai Wang, Aasiya Matin, David J Inwards, Thomas M Habermann, Ivana Micallef, Patrick B Johnston, Luis Porrata, Jonas Paludo, Jose Villasboas Bisneto and 6 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Aung M TunDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Yucai WangDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Aasiya MatinDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
David J InwardsDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Thomas M HabermannDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Ivana MicallefDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Patrick B JohnstonDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Luis PorrataDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Jonas PaludoDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Jose Villasboas BisnetoDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Allison RosenthalInternal Medicine, Division of Hematology/Oncology, Mayo Clinic Arizona, Scottsdale, AZ, USA.
Han W TunDivision of Hematology-Oncology and Blood and Marrow Transplantation and Cellular Therapy Program, Mayo Clinic, Jacksonville, FL, USA.
James R CerhanDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Thomas E WitzigDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Grzegorz S NowakowskiDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Stephen M AnsellDivision of Hematology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMayo Clinic in Florida · USUniversity of Kansas · US

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
NCI NIH HHS P30 CA015083
6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) and brentuximab vedotin (BV) are novel agents for classic Hodgkin lymphoma, including relapse after autologous stem cell transplant (ASCT). However, their impact on survival post-ASCT relapse, in comparison with conventional therapy, is less known due to the lack of randomized controlled trials. Clinical characteristics and outcomes of 115 patients with relapse (or progression) after ASCT are studied. After a median follow-up of 8.59 years from post-ASCT relapse, the median progression-free survival (PFS) and overall survival (OS) were 0.91 and 5.07 years, respectively. Median lines of therapy after post-ASCT relapse was 2 (range, 1-12). The median PFS was not reached (NR) versus 1.11 versus 0.50 versus 0.85 versus 0.78 years (

Identifiers

PMID37034004
PMCPMC10079336
OpenAlexW4362634904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.