Evidence map›Paper›PMID 37034002›Full record

ArticleJournal of clinical and translational research2023

Clinical prediction model for pulmonary thrombosis diagnosis in hospitalized patients with SARS-CoV-2 infection.

Anabel Franco-Moreno, David Brown-Lavalle, Nicolás Rodríguez-Ramírez, Candela Muñoz-Roldán, Ana Ignes Rubio-Aguilera, Maria Campos-Arenas, Nuria Muñoz-Rivas, Eva Moya-Mateo, José Manuel Ruiz-Giardín, Virginia Pardo-Guimerá and 5 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical and translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Anabel Franco-MorenoDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
David Brown-LavalleDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Nicolás Rodríguez-RamírezDepartment of Radiology, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Candela Muñoz-RoldánDepartment of Radiology, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Ana Ignes Rubio-AguileraDepartment of Radiology, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Maria Campos-ArenasDepartment of Radiology, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Nuria Muñoz-RivasDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Eva Moya-MateoDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
José Manuel Ruiz-GiardínDepartment of Internal Medicine, Hospital Universitario de Fuenlabrada, Madrid, Spain.
Virginia Pardo-GuimeráDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Mariano Ulla-AnesDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Roberto Pedrero-ToméEPINUT-UCM (Ref. 920325) Investigation Group, Universidad Complutense de Madrid, Madrid, Spain.
Juan Torres-MachoDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Ana Bustamante-FermoselDepartment of Internal Medicine, Hospital Universitario Infanta Leonor-Virgen de la Torre, Madrid, Spain.
Infanta Leonor Thrombosis Research Group
Hospital Universitario Infanta Leonor · ESHospital Universitario de Fuenlabrada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: We aimed to develop a clinical prediction model for pulmonary thrombosis (PT) diagnosis in hospitalized COVID-19 patients. Methods: Non-intensive care unit hospitalized COVID-19 patients who underwent a computed tomography pulmonary angiogram (CTPA) for suspected PT were included in the study. Demographic, clinical, analytical, and radiological variables as potential factors associated with the presence of PT were selected. Multivariable Cox regression analysis to develop a score for estimating the pre-test probability of PT was performed. The score was internally validated by bootstrap analysis. Results: Among the 271 patients who underwent a CTPA, 132 patients (48.7%) had PT. Heart rate >100 bpm (OR = 4.63 [95% CI: 2.30-9.34]; Conclusions: CHEDDAR score can be used to estimate the pre-test probability of PT in hospitalized COVID-19 patients outside the intensive care unit. Relevance for Patients: Developing a new clinical prediction model for PT diagnosis in COVID-19 may help in the triage of patients, and limit unnecessary exposure to radiation and the risk of nephrotoxicity due to iodinated contrast.

Indexed as

Clinical prediction modelComputed tomography pulmonary angiogramCOVID-19DiagnosisPretest probabilityPulmonary thrombosisThromboinflammation

Identifiers

PMID37034002
PMCPMC10075091
OpenAlexW4320009245

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.