Evidence map›Paper›PMID 37033834›Full record

ArticleACS omega2023

Structure-Based Design of Promysalin Analogues to Overcome Mechanisms of Bacterial Resistance.

Andrew R Mahoney, Kelly M Storek, William M Wuest

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Target-Guided Design and Synthesis of Aryl-Functionalized Promysalin Analogs.Chembiochem : a European journal of chemical biology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Andrew R MahoneyDepartment of Chemistry, Emory Univers ity, and Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, Georgia 30322, United States.
Kelly M StorekDepartment of Infectious Diseases, Genentech, Inc. South San Francisco, California 94080, United States.ORCID https://orcid.org/0000-0002-2289-0214
William M WuestDepartment of Chemistry, Emory Univers ity, and Emory Antibiotic Resistance Center, Emory University School of Medicine, Atlanta, Georgia 30322, United States.ORCID https://orcid.org/0000-0002-5198-7744
Emory University · US

Funding

Natural Product-Inspired Approaches Toward The Development Of Antivirulence And Species-Specific InhibitorsR35GM119426 · NIGMS · TEMPLE UNIV OF THE COMMONWEALTH · PI William M Wuest · 2016 to 2026
$4.8M
NIGMS NIH HHS R35 GM119426
6 · The paper itself

Abstract

The search for antibiotics that function through novel mechanisms of action is ongoing, and recent progress in our lab identified the tricarboxylic acid cycle as a viable option. Promysalin is a secondary metabolite capable of species-specific inhibition of

Identifiers

PMID37033834
PMCPMC10077553
OpenAlexW4353032773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.