Evidence map›Paper›PMID 37033822›Full record

ArticleACS omega2023

Interpreting the Therapeutic Efficiency of Multifunctional Hybrid Nanostructure against Glioblastoma.

Zemin Ou, Xinjian Li, Yun You, Dewen Liu, Jinyu Wang

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zemin OuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 10700, China.ORCID https://orcid.org/0000-0003-2719-0548
Xinjian LiInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 10700, China.
Yun YouInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 10700, China.
Dewen LiuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 10700, China.
Jinyu WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 10700, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma is considered the most fatal malignant brain tumor that starts from the central nervous system (CNS), where the blood-brain barrier (BBB) remains the biggest challenge for active targeting of drugs in malignant brain tumor. Thereby, we have designed a paclitaxel PTX@ANG/FA-NPs hybrid novel nanodrug delivery system that can overcome the clinical BBB. The structural and morphological characterization of PTX@ANG/FA-NPs confirmed successful synthesis of nanomicelles with the size range of about 160 to 170 nm. The overall repressive effect of PTX@ANG/FA-NPs on human glioblastoma U251 cells was 1.2-times that of PTX alone.

Identifiers

PMID37033822
PMCPMC10077551

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.