Evidence map›Paper›PMID 37033438›Full record

ArticleRSC advances2023

Injectable, stretchable, toughened, bioadhesive composite hydrogel for bladder injury repair.

Zhouyang Fu, Shuwei Xiao, Pengchao Wang, Jian Zhao, Zhengyun Ling, Ziyan An, Jinpeng Shao, Weijun Fu

Abstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhouyang FuDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0001-7230-3738
Shuwei XiaoDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0002-8206-538X
Pengchao WangMedical School of Chinese PLA Beijing 100853 China.ORCID https://orcid.org/0000-0002-0495-9425
Jian ZhaoDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0001-7466-027X
Zhengyun LingDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0003-2934-5347
Ziyan AnDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0002-6054-1015
Jinpeng ShaoDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0002-9592-4235
Weijun FuDepartment of Urology, The Third Medical Centre, Chinese PLA General Hospital Beijing 100853 China fuweijun@hotmail.com.ORCID https://orcid.org/0000-0001-6904-7497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The bladder is exposed to constant internal and external mechanical forces due to its deformation and the dynamic environment in which it is placed, which can hamper its repair after an injury. Traditional hydrogel materials have limitations regarding their use in the bladder owing to their poor mechanical and tissue adhesion properties. In this study, a composite hydrogel composed of methacrylate gelatine, methacrylated silk fibroin, and Pluronic F127 diacrylate was developed, which combines the characteristics of natural and synthetic polymers. The mechanical properties of the novel hydrogel, such as stretchability, viscoelasticity, and toughness, were improved by virtue of a particular molecular design strategy whereby covalent and non-covalent bond interactions create a cross-linking effect. In addition, the composite hydrogel has important usability properties; it can be injected in liquid format and rapidly transformed into a gel

Identifiers

PMID37033438
PMCPMC10076968

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.