Evidence map›Paper›PMID 37033240›Full record

ArticleFrontiers in endocrinology2023

Deep learning-based artificial intelligence model for classification of vertebral compression fractures: A multicenter diagnostic study.

Fan Xu, Yuchao Xiong, Guoxi Ye, Yingying Liang, Wei Guo, Qiuping Deng, Li Wu, Wuyi Jia, Dilang Wu, Song Chen and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Deep learning radiomics model based on contrast-enhanced MRI for distinguishing between tuberculous spondylitis and pyogenic spondylitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  3. Article
  4. The Application of Artificial Intelligence in Spine Surgery: A Scoping Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  5. Integrating blockchain technology with artificial intelligence for the diagnosis of tibial plateau fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Detection and Localization of Spine Disorders from Plain Radiography.Journal of imaging informatics in medicine · 2024
    Article
  10. Development and reporting of artificial intelligence in osteoporosis management.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Fan XuDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Yuchao XiongDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Guoxi YeDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Yingying LiangDepartment of Radiology, Guangzhou First People's Hospital, Guangzhou, Guangdong, China.
Wei GuoDepartment of Radiology, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, Hubei, China.
Qiuping DengDepartment of Radiology, Hubei 672 Integrated Traditional Chinese and Western Medicine Orthopedic Hospital, Wuhan, Hebei, China.
Li WuDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Wuyi JiaDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Dilang WuDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Song ChenDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Zhiping LiangDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Xuwen ZengDepartment of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University), Guangzhou, China.
Jinan University · CNGuangzhou First People's Hospital · CNHubei 672 Orthopedics Hospital of Traditional Chinese Medicine and Western Medicine · CNWuhan Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To develop and validate an artificial intelligence diagnostic system based on X-ray imaging data for diagnosing vertebral compression fractures (VCFs). Methods: In total, 1904 patients who underwent X-ray at four independent hospitals were retrospectively (n=1847) and prospectively (n=57) enrolled. The participants were separated into a development cohort, a prospective test cohort and three external test cohorts. The proposed model used a transfer learning method based on the ResNet-18 architecture. The diagnostic performance of the model was evaluated using receiver operating characteristic curve (ROC) analysis and validated using a prospective validation set and three external sets. The performance of the model was compared with three degrees of musculoskeletal expertise: expert, competent, and trainee. Results: The diagnostic accuracy for identifying compression fractures was 0.850 in the testing set, 0.829 in the prospective set, and ranged from 0.757 to 0.832 in the three external validation sets. In the human and deep learning (DL) collaboration dataset, the area under the ROC curves(AUCs) in acute, chronic, and pathological compression fractures were as follows: 0.780, 0.809, 0.734 for the DL model; 0.573, 0.618, 0.541 for the trainee radiologist; 0.701, 0.782, 0.665 for the competent radiologist; 0.707,0.732, 0.667 for the expert radiologist; 0.722, 0.744, 0.610 for the DL and trainee; 0.767, 0.779, 0.729 for the DL and competent; 0.801, 0.825, 0.751 for the DL and expert radiologist. Conclusions: Our study offers a high-accuracy multi-class deep learning model which could assist community-based hospitals in improving the diagnostic accuracy of VCFs.

Indexed as

Bone Diseases, MetabolicDeep LearningFractures, CompressionSpinal FracturesArtificial IntelligenceHumansRetrospective StudiesCNNDL: deep learningDR: digital radiographyvertebral compression fracturesx-ray

Identifiers

PMID37033240
PMCPMC10073698
OpenAlexW4353081113

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.