ArticleFrontiers in pediatrics2023
Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study.
Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Lexical analysis of terms related to nursing care for pregnant women with syphilis.Revista da Escola de Enfermagem da U S P · 2026Article
- Spatial analysis of mortality due to congenital syphilis in Brazil from 2008 to 2022.PloS one · 2026Article
- Trends in Congenital Syphilis Incidence and Mortality in Brazil's Southeast Region: A Time-Series Analysis (2008-2022).Epidemiologia (Basel, Switzerland) · 2025Article
- Construction and validation of an evaluation instrument for the care pathway of people with syphilis.Revista brasileira de enfermagem · 2025Article
- Evaluating the prevalence and adequate treatment for congenital syphilis in a Brazilian reference maternity hospital.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025Observational
- Detection of gestational and congenital syphilis in Paraná state, Brazil, 2007-2021: a time series analysis.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2024Article
- Subnational certification of elimination of mother-to-child transmission of HIV and/or syphilis: a Brazilian experience report.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: The study aimed to analyze the temporal trend of congenital syphilis in Brazil in the period from 2008 to 2018 and its spatial distribution in the Immediate Regions of Urban Articulation, and to identify spatial correlations with socioeconomic factors and prenatal care. Methods: Spatial correlations between the incidence of congenital syphilis and socioeconomic conditions and access to prenatal care were assessed. This ecological study conducted a time series analysis in Brazil and spatial analysis in 482 Immediate Regions of Urban Articulation. Cases of congenital syphilis reported in the Notifiable Diseases Information System and the Live Birth Information System from January 1, 2008, to December 31, 2018 were included. Socioeconomic conditions (percentage of individuals with inadequate water supply and sanitation) were extracted from the 2010 census, whereas the Live Birth Information System provided data on access to prenatal care (percentage of live births with 1-3 prenatal care appointments). The Joinpoint Regression software performed the temporal trend analysis, while the GeoDa software assessed territorial clusters using the Moran's Results: The incidence of congenital syphilis showed an upward trend (annual percent change 1 = 26.96; 95% CI: 18.2-36.3; annual percent change 2 = 10.25; 95% CI: 2.7-28.4) and was unevenly distributed across Immediate Regions of Urban Articulation in Brazil (Moran's Conclusion: Agrowth trend of congenital syphilis in Brazil was observed between 2008 and 2018. Moreover, inequalities in socioeconomic conditions and access to prenatal care influenced the spatial distribution of this disease.
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