Evidence map›Paper›PMID 37033123›Full record

ArticleInternational journal of women's health2023

Risk of Global Developmental Delay in Infants Born from Mothers with COVID-19: A Cross-Sectional Study.

Pedro Ykaro Fialho Silva, Maria Clara Lima da Cruz, Ingrid Guerra Azevedo, Rafaela Silva Moreira, Klayton Galante Sousa, Silvana Alves Pereira

Open access · goldAbstract read
In one paragraph

Article in International journal of women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Pedro Ykaro Fialho SilvaPhysical Therapy Department, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0001-7397-9043
Maria Clara Lima da CruzPhysical Therapy Department, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0001-5882-0712
Ingrid Guerra AzevedoDirección de Investigación, Universidad Católica de Temuco, Temuco, La Araucania, Chile.ORCID 0000-0001-7305-7583
Rafaela Silva MoreiraPhysical Therapy Department, Universidade Federal de Santa Catarina, Araranguá, Santa Catarina, Brazil.ORCID 0000-0003-1973-834X
Klayton Galante SousaPhysical Therapy Department, Faculdade de Ciências da Saúde do Trairí, Universidade Federal do Rio Grande do Norte, Santa Cruz, Rio Grande do Norte, Brazil.ORCID 0000-0002-7710-7522
Silvana Alves PereiraPhysical Therapy Department, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0002-6226-2837
Universidade Federal do Rio Grande do Norte · BRUniversidad Católica de Temuco · CLUniversidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the risk of global developmental delay in infants born from mothers with COVID-19. Patients and Methods: A cross-sectional study was conducted between March and November 2021, with 54 infants of both sexes aged between 1 and 12 months. Twenty-seven infants born from mothers diagnosed with COVID-19 during pregnancy composed the COVID-19 group, whereas infants born from mothers not exposed to COVID-19 composed the control group. Medical records and child health booklets provided neonatal and prenatal data. The Survey of Wellbeing of Young Children screened the risk of global developmental delay during a phone interview or home visit. Chi-squared, Mann-Whitney test, and binary logistic regression were applied. Results: The risk of motor developmental delay was identified in 15 infants (12 in the COVID-19 group), while 36 were at risk of behavioral alteration (22 in the COVID-19 group). The COVID-19 group presented a 6.3-fold risk of motor developmental delay. Motor developmental delay was also significantly associated with socioemotional alterations (odds ratio = 6.4, p = 0.01). Regarding families of infants in the COVID-19 group, 63% of the mothers presented risk of depression, 51.9% risk of substance abuse, 40.7% risk of food insecurity, and 7.4% risk of domestic violence. The inflexibility subscale of the survey was a statistically relevant variable for the socioemotional domain. Conclusion: Infants born from mothers with COVID-19 were at high risk of motor developmental delay and socioemotional alterations. Although, this study fills an important gap in the literature regarding the influence of maternal exposure to COVID-19 on infant development, new studies screening families with infants at risk of developmental delay may significantly impact maternal and child health-related indicators, such as physical health, emotional development and social behavior.

Indexed as

COVID-19infant developmentinfant well-being

Identifiers

PMID37033123
PMCPMC10075265
OpenAlexW4362450340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.