SynthesisFrontiers in public health2023
Effectiveness of myopia control interventions: A systematic review of 12 randomized control trials published between 2019 and 2021.
Synthesis in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- The effectiveness of atropine 0.05% eye drops versus placebo on controlling myopia progression among school children in randomized controlled trials: a systematic review and meta analysis.BMC ophthalmology · 2026Pooled it
- A systematic review of the study design and statistical practices in randomized controlled trials on myopia treatment (2019-2023).BMC ophthalmology · 2025Pooled it
- Repeated low-level red-light therapy vs. conventional treatments for myopic control in children: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Effect of daily disposable Defocus Incorporated Soft Contact lens on myopia control: a 1-year multicentre randomised controlled trial.The British journal of ophthalmology · 2026Trial
- Twice versus once daily application of 0.01% atropine for myopia control in children: a randomised controlled trial.Eye (London, England) · 2025Trial
- New design peripheral defocus spectacle lens vs. single-vision for slowing myopia progression in children: randomized controlled trial.Scientific reports · 2025Trial
- Defocus Incorporated Multiple Segments (DIMS) spectacle lenses in UK children: Outcomes from a 2-year multi-site interventional trial.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025Trial
- Impact of wearing dual-focus soft contact lenses on myopia progression: a one-year randomized clinical trial in Chinese school-age children.BMC ophthalmology · 2024Trial
- Eight-Year Post-Trial Outcomes of a Two-Year Clinical Trial of DIMS Spectacle Lenses.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Long-term axial elongation in myopic children wearing DIMS spectacle lenses: an 8-to-10-year observational study.BMJ open ophthalmology · 2026Observational
- Neuro-ophthalmic review on pediatric myopia: Advancing from refraction to a brain-centric model of axial growth.World journal of clinical pediatrics · 2026Review
- Age Modifies the Comparative Effectiveness of DIMS Versus HAL Spectacle Lenses for Myopia Control: A Real-World Study.Translational vision science & technology · 2026Article
- Orthokeratology and retinal risk: a new dimension in myopia control.Translational pediatrics · 2026Article
- Comparison of effectiveness of four myopia control interventions in Chinese children: a real-world retrospective study.Eye and vision (London, England) · 2026Article
- Effectiveness of Low-Dose Atropine Combined With Bright Light Therapy for Controlling Myopic Eye Growth in Schoolchildren: Study Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Design-Dependent Myopia Control in Orthokeratology: Spherical Versus Aspherical Back Optic Zone Profiles.Bioengineering (Basel, Switzerland) · 2026Article
- Management of myopia: a mini-review.Medical hypothesis, discovery & innovation ophthalmology journal · 2026Review
- Effectiveness of orthokeratology in myopia control during COVID-19 home confinement in Shanghai: a retrospective study.BMC ophthalmology · 2025Article
- Efficacy and safety of orthokeratology sequentially combined with escalating atropine concentrations for myopia control in children.Scientific reports · 2025Article
- Myopia Management in Ontario, Canada.Journal of clinical medicine · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study aims to investigate the effectiveness of interventions to control myopia progression. In this systematic review, the primary outcomes were mean differences (MD) between treatment and control groups in myopia progression (D) and axial length (AL) elongation (mm). Results: The following interventions were found to be effective ( Conclusion: Low-dose atropine 0.01% was not effective in reducing AL progression in two studies. Treatment efficacy with low-dose atropine of 0.05% showed good efficacy. Spectacles (HAL and DIMS) and contact lenses (MiSight and Biofinity) may confer a comparable treatment benefit compared to atropine, to slow myopia progression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.