Evidence map›Paper›PMID 37032540›Full record

ArticleJournal of applied clinical medical physics2023

Dual-energy CT-based stopping power prediction for dental materials in particle therapy.

Friderike K Longarino, Christopher Herpel, Thomas Tessonnier, Stewart Mein, Benjamin Ackermann, Jürgen Debus, Franz Sebastian Schwindling, Wolfram Stiller, Andrea Mairani

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Effects of modern aesthetic dental fillings on proton therapy.Physics and imaging in radiation oncology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Friderike K LongarinoClinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Christopher HerpelDepartment of Prosthodontics, Heidelberg University Hospital, Heidelberg, Germany.
Thomas TessonnierHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Stewart MeinHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Benjamin AckermannHeidelberg Ion Beam Therapy Center (HIT), Heidelberg, Germany.
Jürgen DebusClinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Franz Sebastian SchwindlingDepartment of Prosthodontics, Heidelberg University Hospital, Heidelberg, Germany.
Wolfram StillerDiagnostic & Interventional Radiology (DIR), Heidelberg University Hospital, Heidelberg, Germany.
Andrea MairaniDepartment of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.
German Cancer Research Center · DEHeidelberg University · DEHeidelberger Institut für Radioonkologie · DE

Funding

Deutsche ForschungsgemeinschaftHeidelberg University
6 · The paper itself

Abstract

Radiotherapy with protons or light ions can offer accurate and precise treatment delivery. Accurate knowledge of the stopping power ratio (SPR) distribution of the tissues in the patient is crucial for improving dose prediction in patients during planning. However, materials of uncertain stoichiometric composition such as dental implant and restoration materials can substantially impair particle therapy treatment planning due to related SPR prediction uncertainties. This study investigated the impact of using dual-energy computed tomography (DECT) imaging for characterizing and compensating for commonly used dental implant and restoration materials during particle therapy treatment planning. Radiological material parameters of ten common dental materials were determined using two different DECT techniques: sequential acquisition CT (SACT) and dual-layer spectral CT (DLCT). DECT-based direct SPR predictions of dental materials via spectral image data were compared to conventional single-energy CT (SECT)-based SPR predictions obtained via indirect CT-number-to-SPR conversion. DECT techniques were found overall to reduce uncertainty in SPR predictions in dental implant and restoration materials compared to SECT, although DECT methods showed limitations for materials containing elements of a high atomic number. To assess the influence on treatment planning, an anthropomorphic head phantom with a removable tooth containing lithium disilicate as a dental material was used. The results indicated that both DECT techniques predicted similar ranges for beams unobstructed by dental material in the head phantom. When ion beams passed through the lithium disilicate restoration, DLCT-based SPR predictions using a projection-based method showed better agreement with measured reference SPR values (range deviation: 0.2 mm) compared to SECT-based predictions. DECT-based SPR prediction may improve the management of certain non-tissue dental implant and restoration materials and subsequently increase dose prediction accuracy.

Indexed as

Dental ImplantsProton TherapyHumansPhantoms, ImagingProtonsTomography, X-Ray ComputedDental ImplantsProtonsdental materialsdual-energy CTdual-layer spectral CTparticle therapyrange uncertaintystopping power ratiotreatment planning

Identifiers

PMID37032540
PMCPMC10402687
OpenAlexW4362735328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.