SynthesisBMC psychiatry2023
Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis.
Synthesis in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Prevalence and associated factors of post-traumatic stress disorder in pediatric populations in Africa: a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Assessing the Impact of Virtual Reality, Augmented Reality, and Video Games on Improving Post-Traumatic Stress Disorder Symptoms: A Systematic Review and Meta-Analysis.Inquiry : a journal of medical care organization, provision and financingPooled it
- Impact of posttraumatic stress disorder and comorbid psychiatric conditions on suicide reattempts.European journal of psychotraumatology · 2025Trial
- The Emotion and Symptom-Focused Engagement (EASE) Psychotherapeutic Intervention for Parents of Children With Acute Leukemia: A Feasibility Trial.Psycho-oncology · 2025Trial
- Cost-effectiveness of Transcendental Meditation (TM) for treating Post-Traumatic Stress Disorder (PTSD).PloS one · 2025Trial
- Evaluating evidence based options for initial PTSD treatment non-response: A randomized controlled trial protocol.Contemporary clinical trials communications · 2026Article
- Prior Sexual Violence, PTSD Symptoms, and Recovery Trajectories After New Trauma.JAMA psychiatry · 2026Article
- Risk Factors for Posttraumatic Stress Disorder in Mexican Psychiatric Trauma Survivors.Actas espanolas de psiquiatria · 2026Observational
- Posttraumatic stress disorder from early childhood to late adolescence: a resilience-oriented approach to prevention, diagnosis, and clinical management.Discover mental health · 2026Review
- State of the Science: The epidemiology of posttraumatic stress disorder.Journal of traumatic stress · 2026Review
- Risk of all-cause and cause-specific mortality, and suicide attempt in people with anxiety and stress-related disorders: a systematic review, meta-analysis and meta-regression analysis of 165 studies.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- LGBQ+ Veteran and Service Member Health and Health Care: A Scoping Review of Research from 1994 to 2023.Journal of general internal medicine · 2026Article
- Experiences of infertility-related traumatic events and their association with symptoms of Post-Traumatic Stress Disorder (PTSD) and Complex PTSD: results from a mixed-methods online survey.Human reproduction (Oxford, England) · 2026Article
- All-Cause and Cause-Specific Mortality in Patients With Bipolar II Disorder.JAMA network open · 2026Observational
- How segregation, low birth weight, unemployment, and violence link to low life expectancy in Chicago.Health affairs scholar · 2026Article
- Post-traumatic stress disorder and risk of all-cause and cause-specific mortality: a nationwide population and sibling-controlled cohort study in Taiwan.Epidemiology and psychiatric sciences · 2026Article
- PTSD and suPAR: A multicohort investigation of chronic inflammation.Brain, behavior, and immunity · 2026Article
- The aftermath of trauma on resting state source-level MEG microstate dynamics.European journal of psychotraumatology · 2025Article
- Psychometric evaluation of the UCLA PTSD Reaction Index (PTSD RI-5) in a Turkish Clinical sample of trauma-exposed children.European journal of psychotraumatology · 2025Article
- Systemic inflammation and metabolic syndrome components in threshold/subthreshold posttraumatic stress disorder and food addiction in a Polish community sample.European journal of psychotraumatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPosttraumatic Stress Disorder (PTSD) could potentially increase the risk of mortality, and there is a need for a meta-analysis to quantify this association. This study aims to determine the extent to which PTSD is a predictor of mortality.
methodsEMBASE, MEDLINE, and PsycINFO were searched systematically on 12th February 2020, with updated searches conducted in July 2021, and December 2022 (PROSPERO CRD42019142971). Studies involving community-dwelling participants with a diagnosis of PTSD or PTSD symptoms, and a comparator group of individuals without PTSD, and which assessed mortality risk, were included. A random-effects meta-analysis was conducted on studies reporting Odds Ratio (OR), Hazard Ratio (HR), and Risk Ratio (RR), and subgroup analysis was also performed by age, sex, type of trauma experienced, PTSD diagnosis, and cause of death.
resultsA total of 30 eligible studies of mostly good methodological quality were identified, with a total of more than 2.1 million participants with PTSD. The majority of studies involved male-dominated, veteran populations. PTSD was associated with a 47% (95% CI: 1.06-2.04) greater risk of mortality across six studies that reported OR/RR, and a 32% increased risk across 18 studies which reported time to death (HR: 1.32, 95% CI: 1.10-1.59). There was very high study heterogeneity (I
conclusionPTSD is associated with increased mortality risk, however further research is required amongst civilians, involving women, and in individuals from underdeveloped countries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.