Evidence map›Paper›PMID 37031791›Full record

ArticlePhysiology & behavior2023

CO

Marissa Raskin, Cassidy Malone, Emily N Hilz, Jasper A J Smits, Michael J Telch, Michael W Otto, Jason Shumake, Hongjoo J Lee, Marie-H Monfils

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiology & behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. COAddiction biology · 2026
    Article
  2. Associations of COPhysiology & behavior · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marissa RaskinThe University of Texas at Austin, Institute for Neuroscience, United States.
Cassidy MaloneThe University of Texas at Austin, Department of Psychology, United States.
Emily N HilzThe University of Texas at Austin, Department of Psychology, United States.
Jasper A J SmitsThe University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.
Michael J TelchThe University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.
Michael W OttoBoston University, United States.
Jason ShumakeThe University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.
Hongjoo J LeeThe University of Texas at Austin, Institute for Neuroscience, United States; The University of Texas at Austin, Department of Psychology, United States.
Marie-H MonfilsThe University of Texas at Austin, Institute for Neuroscience, United States; The University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States. Electronic address: marie.monfils@utexas.edu.

Funding

PRE-DOCTORAL TRAINING IN INTERDISCIPLINARY NEUROSCIENCET32DA018926 · NIDA · UNIVERSITY OF TEXAS AUSTIN · PI Nace L Golding, AMY LEE · 2004 to 2026
$5.6M
1/2: CO2 Reactivity as a Biomarker of Non-response to Exposure-based TherapyR01MH125951 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI Marie H. Monfils, Jasper Smits · 2022 to 2026
$3.6M
2/2-CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based TherapyR01MH125949 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Michael W. Otto · 2022 to 2026
$2.8M
CO2 reactivity and orexin activation as predictors of extinction phenotype to fear and reward cuesF31AA030936 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI RASKIN, MARISSA RENEE · 2023 to 2024
$90k
NIAAA NIH HHS F31 AA030936NIDA NIH HHS T32 DA018926NIMH NIH HHS R01 MH125949NIMH NIH HHS R01 MH125951
6 · The paper itself

Abstract

Pavlovian conditioning can underly the maladaptive behaviors seen in psychiatric disorders such as anxiety and addiction. In both the lab and the clinic, these responses can be attenuated through extinction learning, but often return with the passage of time, stress, or a change in context. Extinction to fear and reward cues are both subject to these return of behavior phenomena and have overlap in neurocircuitry, yet it is unknown whether they share any common predictors. The orexin system has been implicated in both fear and appetitive extinction and can be activated through a CO

Indexed as

Carbon DioxideExtinction, PsychologicalFearIndividualityOrexinsCarbon DioxideOrexinsAppetitive conditioningCO(2)ExtinctionIndividual differencesOrexin

Identifiers

PMID37031791
PMCPMC10840099

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.