Evidence map›Paper›PMID 37031656›Full record

ArticleVirology2023

Isolation of a rhesus calicivirus that can replicate in human cells.

Tianyu Gan, Lindsay Droit, Susan Vernon, Dan H Barouch, David Wang

Open access · greenAbstract read
In one paragraph

Article in Virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tianyu GanDepartment of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, 63110, USA.
Lindsay DroitDepartment of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, 63110, USA.
Susan VernonDepartment of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, 63110, USA.
Dan H BarouchCenter for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, 02115, USA.
David WangDepartment of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, 63110, USA; Department of Pathology & Immunology, School of Medicine, Washington University in St. Louis, St. Louis, MO, 63110, USA. Electronic address: davewang@wustl.edu.
Washington University in St. Louis · USBeth Israel Deaconess Medical Center · US

Funding

Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID)RC2DK116713 · NIDDK · WASHINGTON UNIVERSITY · PI WANG, DAVID · 2019 to 2023
$8.9M
NIDDK NIH HHS RC2 DK116713
6 · The paper itself

Abstract

Recoviruses (rhesus enteric caliciviruses) are members of the Caliciviridae family. They are a valuable model for studying human caliciviruses such as noroviruses. It has been suggested that some recoviruses may infect humans, which necessitates detailed studies on the cell type tropism of recoviruses. For the recoviruses that have been cultured to date, successful growth has only been reported in monkey kidney cell lines, precluding their use to study virus interactions with human cells. We isolated and characterized a new recovirus, Recovirus Mo/TG30/2012, from monkey stool which grew efficiently in the monkey kidney cell line LLC-MK2. Notably, the virus can infect and replicate in several human cell lines derived from different organs. The ability to infect a human cell culture system with a recovirus expands our understanding of the potential for spillover to humans as well as increases the value of recoviruses as a model of human caliciviruses.

Indexed as

CaliciviridaeCaliciviridae InfectionsNorovirusRNA VirusesCell LineHumansIntestine, SmallHuman cell cultureIsolationRecovirusTropism

Identifiers

PMID37031656
PMCPMC10264158
OpenAlexW4362447391

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.