ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2023
Updated normative data for the EORTC QLQ-C30 in the general Dutch population by age and sex: a cross-sectional panel research study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
- Eight-year follow-up of patient-reported outcomes in patients with breast cancer participating in exercise studies during chemotherapy.Journal of cancer survivorship : research and practice · 2026Trial
- Effects of physical exercise during adjuvant chemotherapy for breast cancer on long-term tested and perceived cognition: results of a pragmatic follow-up study.Breast cancer research and treatment · 2024Trial
- Quality of life assessment for colorectal cancer follow-up: A latent profile analysis of EORTC measures.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Health-related quality of life after definitive chemoradiotherapy in patients with esophageal carcinoma: a population-based analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Health-related Quality of Life in Localized and Metastatic Renal Cell Carcinoma: Insights from Patient-reported Outcome Measures.European urology open science · 2026Article
- One size does not fit all: data-driven insights of patient-reported outcomes to tailor supportive care in breast cancer.Breast cancer research : BCR · 2026Article
- Longitudinal health-related quality of life profiles in esophageal cancer: insights from a nationwide prospective observational cohort study.Journal of cancer survivorship : research and practice · 2026Article
- Quality of Life in Patients with Chronic Pancreatitis after Frey's Procedure at Tertiary Care Centre: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Quality of life, neurocognitive functioning, psychological issues, sexuality and comorbidity more than 2 years after commencing immune checkpoint inhibitor treatment.Journal for immunotherapy of cancer · 2025Article
- Quality of life and survival in patients with uterine carcinosarcoma: A tertiary center observational study.Gynecologic oncology reports · 2025Article
- Article
- Financial difficulties experienced by patients with gastrointestinal stromal tumours (GIST) in the Netherlands: data from a cross-sectional multicentre study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Development and validation of TreatHSP-QoL: a patient-reported outcome measure for health-related quality of life in hereditary spastic paraplegia.Orphanet journal of rare diseases · 2024Article
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5 authors.
Funding
Abstract
purposeThe European Organisation for Research and Treatment of Cancer (EORTC) quality of life core questionnaire (QLQ-C30) is a validated and widely-used Patient-Reported Outcome Measure for measuring the health-related quality of life (HRQoL) of cancer patients. To facilitate interpretation of results obtained in studies using the EORTC QLQ-C30, we generated normative data for the Dutch general population, stratified by age and sex.
methodsDutch participants were selected from a larger cross-sectional online panel research study collecting EORTC QLQ-C30 general population normative data across 15 countries. EORTC QLQ-C30 raw scores based on a 4-point response scale were transformed to linear scores ranging from 0 to 100. Transformed scores were weighted based on the United Nations population distribution statistics and presented by age and sex/age. Differences in scale scores of ≥ 10 points in HRQoL were applied to indicate clinical relevance.
resultsOne thousand respondents completed the online survey. Stratified by age, clinically meaningful differences were observed, with worse physical functioning scores and better emotional functioning scores with increased age. Symptom scores remained stable across age groups, except for small age differences observed for fatigue, nausea/vomiting, diarrhoea, and financial difficulties. Stratified by sex/age, men generally scored better for both functioning and symptoms. However, these differences were not clinically meaningful.
conclusionsThese updated normative EORTC QLQ-C30 for the Dutch general population can be used to better interpret HRQoL data obtained from Dutch cancer patients. Being part of a larger international study, these data can further be used for inter-country comparisons in multi-national studies.
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