Evidence map›Paper›PMID 37031408›Full record

GuidelineGenetics in medicine : official journal of the American College of Medical Genetics2023

Contributions from medical geneticists in clinical trials of genetic therapies: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG).

Loren D M Peña, Lindsay C Burrage, Gregory M Enns, Edward D Esplin, Cary Harding, Jerry R Mendell, Zhiyv Neal Niu, Curt Scharfe, Timothy Yu, Dwight D Koeberl and 1 more

Abstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Genetics in medicine : official journal of the American College of Medical Genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Loren D M PeñaDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.
Lindsay C BurrageDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; Texas Children's Hospital, Houston, TX.
Gregory M EnnsDepartment of Pediatrics, Stanford University, Stanford, CA.
Edward D EsplinInvitae, San Francisco, CA.
Cary HardingSchool of Medicine, Oregon Health & Science University, Portland, OR.
Jerry R MendellDepartment of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH; Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH.
Zhiyv Neal NiuDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Curt ScharfeDepartment of Genetics, Yale School of Medicine, New Haven, CT.
Timothy YuDivision of Genetics and Genomics, Boston Children's Hospital, Boston, MA; Harvard Medical School, Boston, MA.
Dwight D KoeberlDivision of Medical Genetics, Department of Pediatrics, Duke University, Durham, NC.
ACMG Therapeutics Committee. Electronic address: documents@acmg.netAmerican College of Medical Genetics and Genomics, Bethesda, MD.

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
NCATS NIH HHS UL1 TR002553
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetics, MedicalGenetic TestingGenetic TherapyGenomicsHumansUnited StatesDrug developmentDrug toxicityGene therapyGenetic diseaseLong-term follow-up

Identifiers

PMID37031408
PMCPMC11040261

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.