Evidence map›Paper›PMID 37031040›Full record

ArticleAmerican journal of surgery2023

Outcomes for patients with dementia undergoing emergency and elective colorectal surgery: A large multi-institutional comparative cohort study.

Clancy J Clark, Rachel Adler, Lingwei Xiang, Samir K Shah, Zara Cooper, Dae Hyun Kim, Kueiyu Joshua Lin, John Hsu, Stuart Lipsitz, Joel S Weissman

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in American journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Dementia Is Associated With Adverse Outcomes After Nonruptured Abdominal Aortic Aneurysm Repair.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Clancy J ClarkDivision of Surgical Oncology, Department of General Surgery, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA. Electronic address: cjclark@wakehealth.edu.
Rachel AdlerCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Lingwei XiangCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Samir K ShahDivision of Vascular Surgery, Department of General Surgery, University of Florida, Gainesville, FL, USA.
Zara CooperCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Dae Hyun KimHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, USA.
Kueiyu Joshua LinDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
John HsuCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Stuart LipsitzCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Joel S WeissmanCenter for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA.
Brigham and Women's Hospital · USAtrium Health Wake Forest Baptist · USHarvard University · USUniversity of Florida · US

Funding

Tradeoffs in the Design of Public Long-Term Care BenefitsP01AG032952 · NIA · HARVARD MEDICAL SCHOOL · PI Bruce E. Landon · 2009 to 2026
$39.0M
Understanding and Improving Surgical Decision-Making for Persons Living with Dementia, their Family Caregivers, and their Providers: A Mixed Methods StudyR01AG067507 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI WEISSMAN, JOEL S. · 2020 to 2024
$4.4M
Impact of the COVID-19 Pandemic on Patients with Alzheimer's Disease and Alzheimer's Disease Related DementiasU01AG076478 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HSU, JOHN · 2021 to 2025
$4.1M
Applications of Claims-Based Frailty Index to Advance Evidence for Frailty-Guided Decision-Making - Extension to ADRDR01AG071809 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI KIM, DAE HYUN · 2021 to 2025
$3.5M
Prospective Monitoring of Newly Approved Cardiovascular Drugs in Older Adults with FrailtyR01AG062713 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI KIM, DAE HYUN · 2019 to 2022
$2.8M
Epidemiology and Risk of Antipsychotic Use in Hospitalized Elderly with DeliriumR01AG056368 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI KIM, DAE HYUN · 2018 to 2020
$1.8M
Mid-Career Mentoring Award For Patient-Oriented Research in Frailty and Health OutcomesK24AG073527 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI Dae Hyun Kim · 2022 to 2026
$862k
Restricted Mean Survival Time to Interpret Clinical Trials for Treatment Decision-Making in Older AdultsR21AG060227 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI KIM, DAE HYUN · 2019 to 2020
$449k
NIA NIH HHS K24 AG073527NIA NIH HHS P01 AG032952NIA NIH HHS R01 AG056368NIA NIH HHS R01 AG062713NIA NIH HHS R01 AG067507NIA NIH HHS R01 AG071809NIA NIH HHS R21 AG060227NIA NIH HHS U01 AG076478
6 · The paper itself

Abstract

backgroundAlzheimer's Disease and Related Dementias (ADRD) may result in poor surgical outcomes. The current study aims to characterize the risk of ADRD on outcomes for patients undergoing colorectal surgery.

methodsColorectal surgery patients with and without ADRD from 2007 to 2017 were identified using electronic health record-linked Medicare claims data from two large health systems. Unadjusted and adjusted analyses were performed to evaluate postoperative outcomes.

results5926 patients (median age 74) underwent colorectal surgery of whom 4.8% (n = 285) had ADRD. ADRD patients were more likely to undergo emergent operations (27.7% vs. 13.6%, p < 0.001) and be discharged to a facility (49.8% vs 28.9%, p < 0.001). After multi-variable adjustment, ADRD patients were more likely to have complications (61.1% vs 48.3%, p < 0.001) and required longer hospitalization (7.1 vs 6.1 days, p = 0.001).

conclusionsThe diagnosis of ADRD is an independent risk factor for prolonged hospitalization and postoperative complications after colorectal surgery.

Indexed as

Alzheimer DiseaseColorectal SurgeryDementiaAgedCohort StudiesHumansMedicareUnited StatesAlzheimer's diseaseColectomyDementiaProctectomyTotal abdominal colectomy

Identifiers

PMID37031040
PMCPMC10330079
OpenAlexW4360955475

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.