Evidence map›Paper›PMID 37030428›Full record

ArticleThe Annals of thoracic surgery2024

Outcomes of Surgical Repair of Aberrant Subclavian Arteries in Adults.

Elaine M Griffeth, Elizabeth H Stephens, Joseph A Dearani, Christopher Francois, Austin Todd, William R Miranda, Heidi M Connolly, Crystal R Bonnichsen, Alberto Pochettino

Open access · bronzeAbstract read
In one paragraph

Article in The Annals of thoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Elaine M GriffethDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
Elizabeth H StephensDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota. Electronic address: stephens.elizabeth@mayo.edu.
Joseph A DearaniDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
Christopher FrancoisDepartment of Radiology, Mayo Clinic, Rochester, Minnesota.
Austin ToddDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.
William R MirandaDivision of Structural Heart Disease, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Heidi M ConnollyDivision of Structural Heart Disease, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Crystal R BonnichsenDivision of Structural Heart Disease, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Alberto PochettinoDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USMayo Clinic in Florida · US

Funding

Mayo Clinic StARR ProgramR38HL150086 · NHLBI · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC, KARL A. NATH · 2020 to 2026
$2.5M
NHLBI NIH HHS R38 HL150086
6 · The paper itself

Abstract

backgroundSymptoms, imaging characteristics, and early and midterm surgical outcomes for aberrant subclavian arteries (ASCA) are not well defined in the adult population.

methodsA single-institution retrospective review was conducted of adults undergoing surgical repair of ASCA and descending aorta origin/Kommerell diverticulum (KD) from January 1, 2002, to December 31, 2021. Symptom improvement and differences in imaging characteristics between anatomic groups and the number of symptoms were assessed.

resultsMean age was 46 ± 17 years. There were 23 of 37 left aortic arches with right ASCA (62%) and 14 of 37 right aortic arches with left ASCA (38%). Of these, 31 of 37 (84%) were symptomatic, and 19 of 37 (51%) had KD size/growth meeting criteria for surgical repair. KD aortic origin diameter was larger in more symptomatic patients: 20.60 mm (interquartile range [IQR], 16.42-30.68 mm) in patients with ≥3 symptoms vs 22.05 mm (IQR, 17.52-24.21 mm) for 2 symptoms vs 13.72 mm (IQR, 12.70-15.95 mm) for 1 symptom (P = .018). Aortic replacement was required in 22 of 37 (59%). There were no early deaths. Complications occurred in 11 of 37 (30%): vocal cord dysfunction (4 of 37 [11%]), chylothorax (3 of 37 [8%]), Horner syndrome (2 of 37 [5%]), spinal deficit (2 of 37 [5%]), stroke (1 of 37 [3%]), and temporary dialysis requirement (1 of 37 [3%]). Over a median follow-up of 2.3 years (IQR, 0.8-3.9 years), there was 1 endovascular reintervention and no reoperations. Dysphagia and shortness of breath resolved in 92% and 89%, respectively, whereas gastroesophageal reflux persisted in 47%.

conclusionsThe KD aortic origin diameter correlates with the number of symptoms, and surgical repair of ASCA and descending aorta origin/KD effectively relieves symptoms, with low rates of reintervention. Given the operative complexity, surgical repair should be performed in patients meeting size criteria or with significant dysphagia or shortness of breath symptoms.

Indexed as

Aortic Arch SyndromesBlood Vessel Prosthesis ImplantationCardiovascular AbnormalitiesDeglutition DisordersDiverticulumEndovascular ProceduresAdultAorta, ThoracicDyspneaHumansMiddle AgedRetrospective StudiesSubclavian ArteryTreatment Outcome

Identifiers

PMID37030428
PMCPMC10556195
OpenAlexW4362660534

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.