Evidence map›Paper›PMID 37029714›Full record

Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2023

Preliminary Efficacy of a Theory-Informed Intervention to Increase COVID-19 Testing Uptake Among People Who Inject Drugs in San Diego County: Findings From a Pilot Randomized Controlled Trial.

Angela R Bazzi, Daniela Abramovitz, Alicia Harvey-Vera, Tara Stamos-Buesig, Carlos F Vera, Irina Artamonova, Jenna Logan, Thomas L Patterson, Steffanie A Strathdee

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angela R BazziHerbert Wertheim School of Public Health, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-6828-1919
Daniela AbramovitzDepartment of Medicine, School of Medicine, University of California, San Diego; La Jolla, CA, USA.ORCID 0000-0002-2969-7193
Alicia Harvey-VeraDepartment of Medicine, School of Medicine, University of California, San Diego; La Jolla, CA, USA.ORCID 0000-0002-8708-8169
Tara Stamos-BuesigOnPoint, Harm Reduction Coalition of San Diego, San Diego, CA, USA.
Carlos F VeraDepartment of Medicine, School of Medicine, University of California, San Diego; La Jolla, CA, USA.
Irina ArtamonovaDepartment of Medicine, School of Medicine, University of California, San Diego; La Jolla, CA, USA.
Jenna LoganOnPoint, Harm Reduction Coalition of San Diego, San Diego, CA, USA.
Thomas L PattersonDepartment of Psychiatry, University of California San Diego, CA, USA.ORCID 0000-0003-2311-6164
Steffanie A StrathdeeDepartment of Medicine, School of Medicine, University of California, San Diego; La Jolla, CA, USA.ORCID 0000-0002-7724-691X

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SONIA JAIN · 1994 to 2026
$78.4M
Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Marketsand Drug TourismR01DA049644 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2020 to 2024
$8.2M
Preventing HIV infection among people who inject drugs during COVID-19K01DA043412 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAZZI, ANGELA ROBERTSON · 2017 to 2021
$934k
NCATS NIH HHS UL1 TR001442NIAID NIH HHS P30 AI036214NIDA NIH HHS K01 DA043412NIDA NIH HHS R01 DA049644
6 · The paper itself

Abstract

backgroundPeople who inject drugs (PWID) have low rates of COVID-19 testing yet are vulnerable to severe disease. In partnership with a mobile syringe service program (SSP) in San Diego County, CA, we developed the evidence-, community-, and Social Cognitive Theory-informed "LinkUP" intervention (tailored education, motivational interviewing, problem-solving, and planning) to increase COVID-19 testing uptake among PWID. PURPOSE: To assess preliminary efficacy of LinkUP in increasing PWID COVID-19 testing in a pilot randomized controlled trial (RCT).

methodsWe referred participants (PWID, ≥18 years old, San Diego County residents who had not recently undergone voluntary COVID-19 testing) to mobile SSP sites that had been randomized (by week) to offer the active LinkUP intervention or didactic attention-control conditions delivered by trained peer counselors. Following either condition, counselors offered on-site rapid COVID-19 antigen testing. Analyses estimated preliminary intervention efficacy and explored potential moderation.

resultsAmong 150 participants, median age was 40.5 years, 33.3% identified as Hispanic/Latinx, 64.7% were male, 73.3% were experiencing homelessness, and 44.7% had prior mandatory COVID-19 testing. The LinkUP intervention was significantly associated with higher COVID-19 testing uptake (p < .0001). Homelessness moderated intervention effects; LinkUP increased COVID-19 testing uptake more among participants experiencing homelessness (adjusted risk ratio [aRR]: 1.80; 95% CI: 1.56-2.09; p < .0001) than those not experiencing homelessness (aRR: 1.20; 95% CI: 1.01-1.43; p = .04).

conclusionsFindings from this pilot RCT support the preliminary efficacy of the "LinkUP" intervention to increase COVID-19 testing among PWID and underscore the importance of academic-community partnerships and prevention service delivery through SSPs and other community-based organizations serving vulnerable populations.

Indexed as

COVID-19Drug UsersSubstance Abuse, IntravenousAdolescentAdultCOVID-19 TestingFemaleHumansMalePharmaceutical PreparationsPilot ProjectsPharmaceutical PreparationsCOVID-19 testingHarm reductionIntravenousMotivational interviewingSARS-CoV-2Substance useVulnerable populations

Identifiers

PMID37029714
PMCPMC10205139

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.