Evidence map›Paper›PMID 37029658›Full record

ArticleExperimental physiology2023

Contribution of sensory nerves to cutaneous reactive hyperaemia in non-Hispanic Black and White young adults.

Casey G Turner, Demetria C Walker, Brett J Wong

Open access · diamondAbstract read
In one paragraph

Article in Experimental physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Casey G TurnerDepartment of Kinesiology & Health, Georgia State University, Atlanta, Georgia, USA.
Demetria C WalkerDepartment of Kinesiology & Health, Georgia State University, Atlanta, Georgia, USA.
Brett J WongDepartment of Kinesiology & Health, Georgia State University, Atlanta, Georgia, USA.ORCID 0000-0002-4763-0208
Georgia State University · USTufts Medical Center · US

Funding

Microvascular and sensory nerve function in non-Hispanic Blacks and WhitesR01HL141205 · NHLBI · GEORGIA STATE UNIVERSITY · PI WONG, BRETT · 2018 to 2021
$1.5M
NHLBI NIH HHS R01 HL141205NHLBI NIH HHS R01HL141205
6 · The paper itself

Abstract

NEW

findingsWhat is the central question of this study? Does cutaneous sensory nerve-mediated vasodilatation differ between non-Hispanic Black and White young adults? What is the main finding and its importance? The magnitude of cutaneous reactive hyperaemia is lower in non-Hispanic Black relative to non-Hispanic White young adults, but the overall sensory nerve contribution is the same, suggesting that sensory nerve function is similar in both non-Hispanic Black and White young adults. ABSTRACT: The aim of this study was to assess cutaneous sensory nerve function, independent of nitric oxide, in non-Hispanic Black and White young adults. We tested the hypothesis that cutaneous reactive hyperaemia and sensory nerve-mediated vasodilatation would be lower in non-Hispanic Black young adults relative to non-Hispanic White young adults. Twenty-four participants who self-identified as non-Hispanic Black (n = 12) or non-Hispanic White (n = 12) were recruited. All participants underwent three bouts of reactive hyperaemia. An index of skin blood flow was measured continuously using laser-Doppler flowmetry at a control site and at a site treated with topical 4% lignocaine to inhibit sensory nerve function. Peak reactive hyperaemia was lower in non-Hispanic Black relative to non-Hispanic White participants (P < 0.001). Total reactive hyperaemia was lower in non-Hispanic Black [mean (SD); control, 4085 (955)%CVC

Indexed as

HyperemiaSensory Receptor CellsBlack or African AmericanHumansLidocaineNitric OxideRegional Blood FlowSkinVasodilationWhiteYoung AdultLidocaineNitric Oxidearterial occlusionhumanmicrovascular function

Identifiers

PMID37029658
PMCPMC10363287
OpenAlexW4362716832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.