Evidence map›Paper›PMID 37029451›Full record

ReviewExperimental dermatology2023

Link between obesity and atopic dermatitis: Does obesity predispose to atopic dermatitis, or vice versa?

Shuyun Yang, Tingting Zhu, Joan S Wakefield, Theodora M Mauro, Peter M Elias, Mao-Qiang Man

Open access · bronzeAbstract readReview
In one paragraph

Review in Experimental dermatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Skin Care Supports Overall Well-Being.Clinical, cosmetic and investigational dermatology · 2025
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Body Mass Index z Scores Correlate with Epidermal Function in Chinese Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Shuyun YangDepartment of Dermatology, The People's Hospital of Baoshan, Baoshan, Yunnan, China.
Tingting ZhuDermatology Service, Veterans Affairs Medical Center San Francisco, and Department of Dermatology, University of California, San Francisco, California, USA.
Joan S WakefieldDermatology Service, Veterans Affairs Medical Center San Francisco, and Department of Dermatology, University of California, San Francisco, California, USA.ORCID 0000-0001-6691-6239
Theodora M MauroDermatology Service, Veterans Affairs Medical Center San Francisco, and Department of Dermatology, University of California, San Francisco, California, USA.ORCID 0000-0003-3623-0070
Peter M EliasDermatology Service, Veterans Affairs Medical Center San Francisco, and Department of Dermatology, University of California, San Francisco, California, USA.ORCID 0000-0002-0069-9064
Mao-Qiang ManDermatology Service, Veterans Affairs Medical Center San Francisco, and Department of Dermatology, University of California, San Francisco, California, USA.ORCID 0000-0002-0957-4903
San Francisco VA Medical Center · US

Funding

Pathogenesis and Therapy of Ichthyosis in Disorders of Lipid MetabolismR01AR061106 · NIAMS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MAURO, THEODORA M · 2012 to 2022
$3.3M
NIAMS NIH HHS R01 AR061106NIH HHS R01 AR061106
6 · The paper itself

Abstract

Two serious health conditions, obesity and atopic dermatitis (AD), share some pathological features such as insulin resistance, leptin resistance and inflammation, and a growing body of evidence suggests a link between obesity and AD. Obesity predisposes an individual to and/or worsens AD, whereas AD increases the risk of obesity. Obesity and AD's interactions are mediated by cytokines, chemokines and immune cells. Obese individuals with AD are more resistant to anti-inflammatory therapy, while weight loss can alleviate AD. In this review, we summarize the evidence linking AD and obesity. We also discuss the pathogenic role of obesity in AD, and vice versa. Because of the connection between these two conditions, mitigation of one could possibly prevent the development of or alleviate the other condition. Effective management of AD and weight loss can enhance the wellness of individuals with both of these conditions. However, proper clinical studies are warranted to validate this speculation.

Indexed as

Dermatitis, AtopicHumansInflammationObesityadipose tissueatopic dermatitiscytokinesobesity

Identifiers

PMID37029451
PMCPMC10524376
OpenAlexW4362716653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.