Evidence map›Paper›PMID 37029385›Full record

ArticleBMC bioinformatics2023

Stack-VTP: prediction of vesicle transport proteins based on stacked ensemble classifier and evolutionary information.

Yu Chen, Lixin Gao, Tianjiao Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC bioinformatics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu ChenCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Lixin GaoCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China.
Tianjiao ZhangCollege of Information and Computer Engineering, Northeast Forestry University, Harbin, China. tianjiaozhang@nefu.edu.cn.
Northeast Forestry University · CN

Funding

Fundamental Research Funds for the Central Universities 2572021BH01National Natural Science Foundation of China 62172087
6 · The paper itself

Abstract

Vesicle transport proteins not only play an important role in the transmembrane transport of molecules, but also have a place in the field of biomedicine, so the identification of vesicle transport proteins is particularly important. We propose a method based on ensemble learning and evolutionary information to identify vesicle transport proteins. Firstly, we preprocess the imbalanced dataset by random undersampling. Secondly, we extract position-specific scoring matrix (PSSM) from protein sequences, and then further extract AADP-PSSM and RPSSM features from PSSM, and use the Max-Relevance-Max-Distance (MRMD) algorithm to select the optimal feature subset. Finally, the optimal feature subset is fed into the stacked classifier for vesicle transport proteins identification. The experimental results show that the of accuracy (ACC), sensitivity (SN) and specificity (SP) of our method on the independent testing set are 82.53%, 0.774 and 0.836, respectively. The SN, SP and ACC of our proposed method are 0.013, 0.007 and 0.76% higher than the current state-of-the-art methods.

Indexed as

AlgorithmsPosition-Specific Scoring MatricesVesicular Transport ProteinsAmino Acid SequenceCarrier ProteinsSupport Vector MachineCarrier ProteinsVesicular Transport ProteinsEnsemble learningProtein predictionStacked modelVesicle transport proteins

Identifiers

PMID37029385
PMCPMC10080812
OpenAlexW4362698482

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.