Evidence map›Paper›PMID 37029242›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

LncRNA CASC19: a novel oncogene involved in human cancer.

Shidong Wang, Chen Qiao, Rui Fang, Shuyue Yang, Guiping Zhao, Si Liu, Peng Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. The ceRNA Regulatory Network in Vitiligo: Evidence from Bioinformatics Analysis.Clinical, cosmetic and investigational dermatology · 2025
    Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shidong WangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Chen QiaoDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Rui FangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Shuyue YangDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Guiping ZhaoDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.
Si LiuDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. liusi@ccmu.edu.cn.
Peng LiDepartment of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China. lipeng@ccmu.edu.cn.ORCID http://orcid.org/0000-0003-2927-2758
Capital Medical University · CN

Funding

Beijing Municipal Administration of Hospitals XXZ0205National Natural Science Foundation of China 82070575Natural Science Foundation of Beijing Municipality J180010
6 · The paper itself

Abstract

Multiple studies have shown that long non-coding RNAs (lncRNAs) play an important role in the occurrence and development of diverse cancers. Cancer susceptibility candidate 19 (CASC19), encoded by chromosome 8q24.21, is a newly discovered lncRNA that contains 324 nucleotides. CASC19 has been found to be significantly overexpressed in different human cancers, such as non-small cell lung carcinoma, gastric cancer, colorectal cancer, pancreatic cancer, clear cell renal cell carcinoma, glioma, cervical cancer, and nasopharyngeal carcinoma. Moreover, dysregulation of CASC19 was closely associated with clinicopathological parameters and cancer progression. CASC19 regulates a variety of cell phenotypes, including cell proliferation, apoptosis, cell cycle, migration, invasion, epithelial-mesenchymal transition, autophagy, and therapeutic resistance. In this study, we review recent studies on the characteristics and biological function of CASC19, as well as its role in human cancers. These findings suggest that CASC19 may be both a reliable biomarker and a potential therapeutic target in cancers.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsRNA, Long NoncodingStomach NeoplasmsCell ProliferationGene Expression Regulation, NeoplasticHumansOncogenesRNA, Long NoncodingBiomarkerCancerCASC19Long non-coding RNATherapeutic target

Identifiers

PMID37029242
OpenAlexW4362705730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.