Evidence map›Paper›PMID 37028679›Full record

ArticleThe Science of the total environment2023

Exposure of adult zebrafish (Danio rerio) to SARS-CoV-2 at predicted environmentally relevant concentrations: Outspreading warns about ecotoxicological risks to freshwater fish.

Thiarlen Marinho da Luz, Abraão Tiago Batista Guimarães, Stênio Gonçalves da Silva Matos, Sindoval Silva de Souza, Alex Rodrigues Gomes, Aline Sueli de Lima Rodrigues, Edison Luiz Durigon, Ives Charlie-Silva, Ítalo Nascimento Freitas, Abu Reza Md Towfiqul Islam and 3 more

RetractedAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in The Science of the total environment, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Zebrafish (International journal of molecular sciences · 2024
    Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Thiarlen Marinho da LuzLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil.
Abraão Tiago Batista GuimarãesLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil.
Stênio Gonçalves da Silva MatosLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil.
Sindoval Silva de SouzaLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil.
Alex Rodrigues GomesLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Aline Sueli de Lima RodriguesLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil.
Edison Luiz DurigonLaboratory of Clinical and Molecular Virology, Institute of Biomedical Sciences, University of São Paulo, Brazil.
Ives Charlie-SilvaChemistry Institute, São Paulo State University (UNESP) - Campus Araraquara, Brazil.
Ítalo Nascimento FreitasLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Abu Reza Md Towfiqul IslamBegum Rokeya University, Department of Disaster Management, Rangpur 5404, Bangladesh.
Md Mostafizur RahmanLaboratory of Environmental Health and Ecotoxicology, Department of Environmental Sciences, Jahangirnagar University, Dhaka 1342, Bangladesh.
Abner Marcelino SilvaLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil.
Guilherme MalafaiaLaboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Brazilian Academy of Young Scientists (ABJC), Brazil. Electronic address: guilhermeifgoiano@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the multifaceted social, economic, and public health impacts associated with the COVID-19 pandemic are known, little is known about its effects on non-target aquatic ecosystems and organisms. Thus, we aimed to evaluate the potential ecotoxicity of SARS-CoV-2 lysate protein (SARS.CoV2/SP02.2020.HIAE.Br) in adult zebrafish (Danio rerio) at predicted environmentally relevant concentrations (0.742 and 2.226 pg/L), by 30 days. Although our data did not show locomotor alterations or anxiety-like or/and anxiolytic-like behavior, we noticed that exposure to SARS-CoV-2 negatively affected habituation memory and social aggregation of animals in response to a potential aquatic predator (Geophagus brasiliensis). An increased frequency of erythrocyte nuclear abnormalities was also observed in animals exposed to SARS-CoV-2. Furthermore, our data suggest that such changes were associated with a redox imbalance [↑ROS (reactive oxygen species), ↑H

Indexed as

COVID-19Water Pollutants, ChemicalAcetylcholinesteraseAnimalsEcosystemFresh WaterHumansOxidative StressPandemicsSARS-CoV-2ZebrafishAcetylcholinesteraseWater Pollutants, ChemicalBiomarkersDanio rerioEcotoxicityEnvironmental toxicologyNew coronavirus

Identifiers

PMID37028679
PMCPMC10076041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.