Evidence map›Paper›PMID 37028579›Full record

SynthesisNeuroscience and biobehavioral reviews2023

A systematic review of associations between emotion regulation characteristics and inflammation.

Daniel P Moriarity, Mora M Grehl, Rachel F L Walsh, Lydia G Roos, George M Slavich, Lauren B Alloy

Abstract readSystematic Review
In one paragraph

Synthesis in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Emotion regulation as a protective factor in the association between stress and inflammation in older adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Lifetime stressor exposure is related to suicidality in autistic adults: A multinational study.Autism : the international journal of research and practice · 2025
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Toward a dynamic immunopsychiatry.Brain, behavior, and immunity · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel P MoriarityDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA. Electronic address: dmoriarity@mednet.ucla.edu.
Mora M GrehlDepartment of Psychology & Neuroscience, Temple University, USA.
Rachel F L WalshDepartment of Psychology & Neuroscience, Temple University, USA.
Lydia G RoosDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA.
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, USA.
Lauren B AlloyDepartment of Psychology & Neuroscience, Temple University, USA.

Funding

Integrated Reward-Inflammation Model Of First Onset Of Major Depression In Adolescence SupplementR01MH123473 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH, NUSSLOCK, ROBIN · 2021 to 2025
$3.8M
Risk for Adolescent Depression: Stress, Cognitive Vulnerability, & InflammationR01MH101168 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2013 to 2017
$3.2M
Testing a Social Safety Theory Perspective on Depression: An Intensive Longitudinal Immunopsychiatric Data ApproachF32MH130149 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MORIARITY, DANIEL P · 2022 to 2024
$210k
Integrated Reward Sensitivity and Rumination Model of Stress Reactivity and Depression SymptomsF31MH122116 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI MORIARITY, DANIEL P · 2020 to 2021
$58k
NIMH NIH HHS F31 MH122116NIMH NIH HHS F32 MH130149NIMH NIH HHS R01 MH101168NIMH NIH HHS R01 MH123473
6 · The paper itself

Abstract

Elevated inflammation is a risk factor for many psychiatric (e.g., depression) and somatic conditions (e.g., rheumatoid arthritis). Inflammation is influenced by psychosocial processes such as emotion regulation. Characterization of which emotion regulation characteristics impact inflammation could help refine psychosocial interventions aimed at normalizing health-harming inflammatory activity for individuals with psychiatric and somatic illnesses. To investigate this issue, we systematically reviewed the literature on associations between a variety of emotion regulation traits and inflammation. Out of 2816 articles identified, 38 were included in the final review. 28 (74%) found that (a) poor emotion regulation is associated with higher inflammation and/or (b) strong emotion regulation skills are associated with lower inflammation. Consistency of results differed as a function of the emotion regulation construct investigated and methodological characteristics. Results were most consistent for studies testing positive coping/social support seeking or broadly defined emotion regulation/dysregulation. Methodologically, studies testing reactivity to a stressor, adopting a vulnerability-stress framework, or using longitudinal data were most consistent. Implications for integrated, transdiagnostic psychoimmunological theories are discussed, as well as recommendations for clinical research.

Indexed as

Emotional RegulationEmotionsHumansInflammationPhenotypeRisk FactorsEmotion regulationHealthImmunologyInflammationStress

Identifiers

PMID37028579
PMCPMC10425218

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.