Evidence map›Paper›PMID 37028521›Full record

ArticleUrology2023

Insurance Type and Area Deprivation Are Associated With Worse Overall Mortality for Patients With Muscle-invasive Bladder Cancer.

David T Miller, Zhaojun Sun, Valentina Grajales, Kelly R Pekala, Kirsten Y Eom, Jonathan Yabes, Benjamin J Davies, Lindsay M Sabik, Bruce L Jacobs

Abstract read
In one paragraph

Article in Urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David T MillerDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: millerdt@upmc.edu.
Zhaojun SunDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Valentina GrajalesDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Kelly R PekalaDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Kirsten Y EomDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Jonathan YabesDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Benjamin J DaviesDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Lindsay M SabikDepartment of Health Policy and Management, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Bruce L JacobsDepartment of Urology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JOHN C. BYRD · 1988 to 2026
$158.0M
NCI NIH HHS P30 CA047904
6 · The paper itself

Abstract

objectiveTo examine the association of area-level socioeconomic status, rural-urban residence, and type of insurance with overall and cancer-specific mortality among patients with muscle-invasive bladder cancer.

methodsUsing the Pennsylvania Cancer Registry, which collects demographic, insurance, and clinical information on every patient with cancer within the state, we identified all patients diagnosed with non-metastatic muscle-invasive bladder cancer between 2010 and 2016 based on clinical and pathologic staging. We used the Area Deprivation Index (ADI) as a surrogate for socioeconomic status and Rural-Urban Commuting Area codes to classify urban, large town, and rural communities. ADI was reported in quartiles, with 4 representing the lowest socioeconomic status. We fit multivariable logistic regression and Cox models to assess the relationship of these social determinants with overall and cancer-specific survival adjusting for age, sex, race, stage, treatment, rural-urban classification, insurance and ADI.

resultsWe identified 2597 patients with non-metastatic muscle-invasive bladder cancer. On multivariable analysis, Medicare (hazards ratio [HR] 1.15), Medicaid (HR 1.38), ADI 3 (HR 1.16) and ADI 4 (HR 1.21) were independent predictors of greater overall mortality (all P < 0.05). Female sex and receipt of non-standard treatment were associated with increased overall mortality and bladder cancer-specific mortality. There was no significant difference in both overall and cancer-specific survival between patients who were non-Hispanic White compared to non-White or between those from urban areas, large towns, or rural locations.

conclusionLower socioeconomic status and Medicare and Medicaid insurance were associated with a greater risk of overall mortality while rural residence was not a significant factor. Implementation of public health programs may help reduce the gap in mortality for low SES at-risk populations.

Indexed as

MedicareUrinary Bladder NeoplasmsAgedFemaleHumansMedicaidMusclesSocial ClassUnited States

Identifiers

PMID37028521
PMCPMC11225579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.