Evidence map›Paper›PMID 37028106›Full record

ArticleDrug and alcohol dependence2023

Inhibitory and excitatory alcohol-seeking cues distinct roles in behavior, neurochemistry, and mesolimbic pathway in alcohol preferring (P) rats.

Sheketha R Hauser, Gerald A Deehan, Christopher P Knight, Robert A Waeiss, Eric A Engleman, Zheng-Ming Ding, Phillip L Johnson, William J McBride, William A Truitt, Zachary A Rodd

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sheketha R HauserDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address: shhauser@iupui.edu.
Gerald A DeehanDepartment of Psychology, East Tennessee State University, Johnson City, TN 37614, USA.
Christopher P KnightDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Robert A WaeissDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Eric A EnglemanDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zheng-Ming DingDepartment of Anesthesiology and Perioperative Medicine, Department of Pharmacology, The Pennsylvania State University, Penn State College of Medicine, Hershey, PA 17033, USA.
Phillip L JohnsonStark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
William J McBrideDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
William A TruittStark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Anatomy, Cell Biology & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zachary A RoddDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Indiana University School of MedicineEast Tennessee State University · USPennsylvania State University · US

Funding

TRAINING GRANT ON GENETICS ASPECTS OF ALCOHOLISMT32AA007462 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CRISTINE L CZACHOWSKI · 1985 to 2026
$10.7M
RAT RESEARCH COMPONENTP50AA007611 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CRABB, DAVID W · 1987 to 2002
$5.3M
NEUROBIOLOGY OF HIGH ALCOHOL SEEKING BEHAVIORR01AA010721 · NIAAA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MCBRIDE, WILLIAM J · 1995 to 2010
$3.1M
7/8 NADIA UO1 Adolescent Alcohol and Neurocircuitry Mediating Ethanol ReinforcementU01AA024612 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI RODD, ZACHARY AARON · 2015 to 2019
$1.6M
Neuronal underpinnings of repeated deprivations on cue-induced alcohol-seekingR01AA022287 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI MCBRIDE, WILLIAM J · 2013 to 2017
$1.5M
Biological Basis of Conditioned Cues Effects on EtOH-SeekingR01AA020908 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI RODD, ZACHARY AARON · 2012 to 2016
$1.5M
NIAAA NIH HHS P50 AA007611NIAAA NIH HHS R01 AA010721NIAAA NIH HHS R01 AA020908NIAAA NIH HHS R01 AA022287NIAAA NIH HHS T32 AA007462NIAAA NIH HHS U01 AA024612
6 · The paper itself

Abstract

Cues associated with alcohol use can readily enhance self-reported cravings for alcohol, which increases the likelihood of reusing alcohol. Understanding the neuronal mechanisms involved in alcohol-seeking behavior is important for developing strategies to treat alcohol use disorder. In all experiments, adult female alcohol-preferring (P) rats were exposed to three conditioned odor cues; CS+ associated with EtOH self-administration, CS- associated with the absence of EtOH (extinction training), and a CS

Indexed as

CuesNeurochemistryAnimalsConditioning, OperantDopamineDrug-Seeking BehaviorEthanolExtinction, PsychologicalFemaleRatsSelf AdministrationDopamineEthanolConditioned cuesEthanol-seekingEthanol self-administrationPavlovian Spontaneous Recovery

Identifiers

PMID37028106
PMCPMC10212692
OpenAlexW4361199851

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.