Evidence map›Paper›PMID 37027782›Full record

ArticleACS nano2023

Accurate Sizing of Nanoparticles Using a High-Throughput Charge Detection Mass Spectrometer without Energy Selection.

Conner C Harper, Zachary M Miller, Matthew S McPartlan, Jacob S Jordan, Randall E Pedder, Evan R Williams

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 31 citations in OpenAlex.

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  7. Single particle charge detection mass spectrometry enables molecular characterization of lipid nanoparticles and mRNA packaging.Journal of controlled release : official journal of the Controlled Release Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Conner C HarperDepartment of Chemistry, University of California, Berkeley, California 94720-1460, United States.
Zachary M MillerDepartment of Chemistry, University of California, Berkeley, California 94720-1460, United States.
Matthew S McPartlanDepartment of Chemistry, University of California, Berkeley, California 94720-1460, United States.
Jacob S JordanDepartment of Chemistry, University of California, Berkeley, California 94720-1460, United States.ORCID 0000-0003-2894-3126
Randall E PedderArdara Technologies LP, Ardara, Pennsylvania 15615, United States.
Evan R WilliamsDepartment of Chemistry, University of California, Berkeley, California 94720-1460, United States.ORCID 0000-0002-1733-3018
University of California, Berkeley · US

Funding

Multiplexed Charge Detection Mass Spectrometer for Extended Mass and Collisional Cross Section MeasurementsR01GM139338 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Evan R Williams · 2020 to 2026
$2.9M
NIGMS NIH HHS R01 GM139338
6 · The paper itself

Abstract

The sizes and shapes of nanoparticles play a critical role in their chemical and material properties. Common sizing methods based on light scattering or mobility lack individual particle specificity, and microscopy-based methods often require cumbersome sample preparation and image analysis. A promising alternative method for the rapid and accurate characterization of nanoparticle size is charge detection mass spectrometry (CDMS), an emerging technique that measures the masses of individual ions. A recently constructed CDMS instrument designed specifically for high acquisition speed, efficiency, and accuracy is described. This instrument does not rely on an ion energy filter or estimates of ion energy that have been previously required for mass determination, but instead uses direct,

Indexed as

chargehigh-throughputmassmeasurementnanoparticleprecisionsizing

Identifiers

PMID37027782
PMCPMC10389270
OpenAlexW4362694293

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.