Evidence map›Paper›PMID 37027460›Full record

ArticleScience advances2023

The histone demethylase Kdm3 prevents auto-immune piRNAs production in

Karine Casier, Julie Autaa, Nathalie Gueguen, Valérie Delmarre, Pauline P Marie, Stéphane Ronsseray, Clément Carré, Emilie Brasset, Laure Teysset, Antoine Boivin

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. piRNA associates with immune diseases.Cell communication and signaling : CCS · 2024
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Karine CasierTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.ORCID 0000-0001-6825-8057
Julie AutaaTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.ORCID 0000-0002-4969-0941
Nathalie GuegueniGReD, CNRS, INSERM, Faculté de Médecine, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.
Valérie DelmarreTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.
Pauline P MarieTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.ORCID 0000-0003-0368-608X
Stéphane RonsserayTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.
Clément CarréTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.
Emilie BrassetiGReD, CNRS, INSERM, Faculté de Médecine, Université Clermont Auvergne, 63000 Clermont-Ferrand, France.ORCID 0000-0003-2479-7969
Laure TeyssetTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.ORCID 0000-0002-7413-1850
Antoine BoivinTransgenerational Epigenetics and Small RNA Biology, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Laboratoire Biologie du Développement, UMR7622, F-75005 Paris, France.ORCID 0000-0001-8671-1599
Centre National de la Recherche Scientifique · FR

Funding

Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
NIGMS NIH HHS R01 GM084947
6 · The paper itself

Abstract

Genome integrity of the animal germline is protected from transposable element activity by PIWI-interacting RNAs (piRNAs). While piRNA biogenesis is intensively explored, little is known about the genetical determination of piRNA clusters, the genomic sources of piRNAs. Using a bimodal epigenetic state piRNA cluster (

Indexed as

DrosophilaDrosophila ProteinsAnimalsDNA Transposable ElementsFemalePiwi-Interacting RNARNA, Small InterferingDNA Transposable ElementsDrosophila ProteinsPiwi-Interacting RNARNA, Small Interfering

Identifiers

PMID37027460
PMCPMC10081847
OpenAlexW4362706225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.