ArticleProceedings of the National Academy of Sciences of the United States of America2023
A shark-inspired general model of tooth morphogenesis unveils developmental asymmetries in phenotype transitions.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 13 citations in OpenAlex.
- Lateral inhibition governs ancestral cellular patterning in fossil and extant liverworts.Development (Cambridge, England) · 2026Article
- Article
- Bounding phenotype transition probabilities via conditional complexity.Journal of the Royal Society, Interface · 2025Article
- Speed-dependent locomotor patterns during steady swimming in a demersal shark.Journal of fish biology · 2025Article
- Comparative transcriptomics in serial organs uncovers early and pan-organ developmental changes associated with organ-specific morphological adaptation.Nature communications · 2025Article
- Quantifying the Denticle Multiverse: A Standardized Coding System to Capture Three Dimensional Morphological Variations for Quantitative Evolutionary and Ecological Studies of Elasmobranch Denticles.Integrative organismal biology (Oxford, England) · 2025Article
- A multiscale computational framework for the development of spines in molluscan shells.PLoS computational biology · 2024Article
- Bias in the arrival of variation can dominate over natural selection in Richard Dawkins's biomorphs.PLoS computational biology · 2024Article
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4 authors at 2 institutions in 1 country.
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Abstract
Developmental complexity stemming from the dynamic interplay between genetic and biomechanic factors canalizes the ways genotypes and phenotypes can change in evolution. As a paradigmatic system, we explore how changes in developmental factors generate typical tooth shape transitions. Since tooth development has mainly been researched in mammals, we contribute to a more general understanding by studying the development of tooth diversity in sharks. To this end, we build a general, but realistic, mathematical model of odontogenesis. We show that it reproduces key shark-specific features of tooth development as well as real tooth shape variation in small-spotted catsharks
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