LatentPCN: latent space-constrained point cloud network for reconstruction of 3D patient-specific bone surface models from calibrated biplanar X-ray images.

purposeAccurate three-dimensional (3D) models play crucial roles in computer assisted planning and interventions. MR or CT images are frequently used to derive 3D models but have the disadvantages that they are expensive or involving ionizing radiation (e.g., CT acquisition). An alternative method based on calibrated 2D biplanar X-ray images is highly desired.

methodsA point cloud network, referred as LatentPCN, is developed for reconstruction of 3D surface models from calibrated biplanar X-ray images. LatentPCN consists of three components: an encoder, a predictor, and a decoder. During training, a latent space is learned to represent shape features. After training, LatentPCN maps sparse silhouettes generated from 2D images to a latent representation, which is taken as the input to the decoder to derive a 3D bone surface model. Additionally, LatentPCN allows for estimation of a patient-specific reconstruction uncertainty.

resultsWe designed and conducted comprehensive experiments on datasets of 25 simulated cases and 10 cadaveric cases to evaluate the performance of LatentLCN. On these two datasets, the mean reconstruction errors achieved by LatentLCN were 0.83 mm and 0.92 mm, respectively. A correlation between large reconstruction errors and high uncertainty in the reconstruction results was observed.

conclusionLatentPCN can reconstruct patient-specific 3D surface models from calibrated 2D biplanar X-ray images with high accuracy and uncertainty estimation. The sub-millimeter reconstruction accuracy on cadaveric cases demonstrates its potential for surgical navigation applications.