ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2023
Association between immediate postoperative hypoalbuminemia and surgical site infection after posterior lumbar fusion surgery.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Systematic review of risk prediction models for surgical site infection after abdominal surgery in adults.Frontiers in public health · 2026Pooled it
- Risk factors for surgical site infections after spinal surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- A predictive nomogram for postoperative pulmonary infection after thoracoscopic surgery in lung cancer.Medicine · 2026Article
- Interpretable machine learning model for predicting postoperative hypoproteinemia in middle-aged and elderly patients following total joint arthroplasty: a multicenter retrospective study.Frontiers in nutrition · 2026Article
- Preoperative albumin-to-fibrinogen ratio as a predictor of postoperative hospital stay in locally advanced esophageal squamous cell carcinoma after neoadjuvant therapy.Scientific reports · 2025Article
- Construction and validation of a nomogram predictive model for assessing the risk of surgical site infections following posterior lumbar fusion surgery.Scientific reports · 2025Article
- Nutritional status is associated with inferior clinical outcomes: A National Surgical Quality Improvement Project analysis of surgically treated spinal vascular lesions.Surgical neurology international · 2025Article
- Risk Factors of Surgical Site Infection After Adult Closed Tibial Plateau Fractures Treated by Open Reduction and Internal Fixation.Infection and drug resistance · 2025Article
- Analysis of the associated factors in postoperative wound infection following open reduction and internal fixation for elbow fracture.International wound journal · 2024Article
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Authors and funding
9 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeIn this study, we intended to investigate the association between immediate postoperative hypoalbuminemia and surgical site infection (SSI), and determine a threshold value for postoperative hypoalbuminemia that can assist in risk stratification in patients after posterior lumbar fusion surgery.
methodsFrom January 2017 to December 2021, 466 consecutive patients who underwent posterior lumbar fusion surgery were selected to analyze the relationship between immediate postoperative hypoalbuminemia and SSI. Multivariate logistic regression analysis was performed to identify the independent risk factors of SSI and postoperative hypoalbuminemia. Receiver Operating Characteristic (ROC) analysis was used to determine the optimal value for postoperative hypoalbuminemia, and subsequent grouping was based on the identified threshold.
resultsOf the total 466 patients, 25 patients (5.4%) developed SSI after surgery, and lower postoperative albumin (OR: 0.716, 95% CI: 0.611-0.840, p < 0.001) was independently associated with SSI. ROC analysis showed that the cutoff value of postoperative hypoalbuminemia was 32 g/L with a sensitivity of 0.760, specificity of 0.844, and a Youden index of 0.604. Postoperative SSI was more common in patients with postoperative hypoalbuminemia than in those without (21.6% vs. 1.6%, p < 0.001). Age, gender and operative duration were found to be independent predictors of postoperative hypoalbuminemia.
conclusionsThis study showed that immediate postoperative hypoalbuminemia was an independent risk factor for the development of SSI in patients who underwent posterior lumbar fusion. Even in patients with a normal preoperative serum albumin level, there was an increased risk of SSI when the postoperative albumin within 24 h was < 32 g/L.
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