Evidence map›Paper›PMID 37026669›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2023

Over One Million DNA and Protein Events Through Ultra-Stable Chemically-Tuned Solid-State Nanopores.

Jugal Saharia, Yapa Mudiyanselage Nuwan Dhananjaya Yapa Bandara, Buddini Iroshika Karawdeniya, Jason Rodger Dwyer, Min Jun Kim

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  6. Article
  7. Accessing robust vaccine coformulation stability by single adjuvant detection on a microelectrode.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jugal SahariaDepartment of Mechanical Engineering, Southern Methodist University, Dallas, TX, 75275, USA.ORCID 0000-0003-1065-4844
Yapa Mudiyanselage Nuwan Dhananjaya Yapa BandaraResearch School of Chemistry, The Australian National University, Canberra, ACT, 2601, Australia.ORCID 0000-0003-1921-8467
Buddini Iroshika KarawdeniyaDepartment of Electronic Materials Engineering, Research School of Physics, The Australian National University, Canberra, ACT, 2601, Australia.ORCID 0000-0002-2733-5973
Jason Rodger DwyerDepartment of Chemistry, University of Rhode Island, 140 Flagg Road, Kingston, RI, 02881, USA.
Min Jun KimDepartment of Mechanical Engineering, Southern Methodist University, Dallas, TX, 75275, USA.ORCID 0000-0002-0819-1644

Funding

Nanotechnology Enabled Selection of MHC-Peptide Ligands to Personalize Cancer TherapyR21CA240220 · NCI · UNIVERSITY OF TEXAS ARLINGTON · PI ALEXANDRAKIS, GEORGIOS · 2020 to 2021
$594k
NCI NIH HHS R21 CA240220
6 · The paper itself

Abstract

Stability, long lifetime, resilience against clogging, low noise, and low cost are five critical cornerstones of solid-state nanopore technology. Here, a fabrication protocol is described wherein >1 million events are obtained from a single solid-state nanopore with both DNA and protein at the highest available lowpass filter (LPF, 100 kHz) of the Axopatch 200B-the highest event count mentioned in literature. Moreover, a total of ≈8.1 million events are reported in this work encompassing the two analyte classes. With the 100 kHz LPF, the temporally attenuated population is negligible while with the more ubiquitous 10 kHz, ≈91% of the events are attenuated. With DNA experiments, the pores are operational for hours (typically >7 h) while the average pore growth is merely ≈0.16 ± 0.1 nm h

Indexed as

NanoporesDNANanotechnologyDNAhigh-lifetimelow-noisemillion eventsnanoporesultra-stable

Identifiers

PMID37026669
PMCPMC10524034

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.